SCHEMBL327614

SCHEMBL327614

CCC(=O)N1CCC(=O)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.47
KMT2A Q03164 2/20 0.42
PKM P14618 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MEN1 O00255 1/20 0.41
TSHR P16473 1/20 0.41
CHRNB2 P17787 3/20 0.41
CHRNA3 P32297 3/20 0.41
CHRNA4 P43681 3/20 0.41
CHRNB3 Q05901 1/20 0.41
CHRNA6 Q15825 1/20 0.41
EPHX2 P34913 3/20 0.41
LMNA P02545 1/20 0.40
CHRNB4 P30926 2/20 0.39
CHRNA7 P36544 2/20 0.39
OPRM1 P35372 1/20 0.39
DRD3 P35462 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
BRD4 O60885 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL655840 0.92 BLM (0.42) BLMKMT2APKMALDH1A1MEN1
SCHEMBL7435719 0.83 L3MBTL1 (0.47) KMT2APKMALDH1A1MEN1CHRNB2
SCHEMBL25630712 0.80 BLM (0.46) BLMKMT2AALDH1A1MEN1TSHR
SCHEMBL2739418 0.80 BLM (0.57) BLMKMT2AALDH1A1MEN1TSHR
SCHEMBL20756575 0.80 BLM (0.57) BLMKMT2AALDH1A1MEN1TSHR
SCHEMBL180620 0.80
SCHEMBL7431273 0.79 L3MBTL1 (0.58) KMT2AMEN1NPC1
Ethylene SCHEMBL8379639 0.79 L3MBTL1 (0.44) KMT2APKMALDH1A1MEN1CHRNB2
SCHEMBL9139551 0.78 L3MBTL1 (0.67) KMT2AALDH1A1MEN1LMNA
SCHEMBL4967184 0.77 KMT2A (0.42) KMT2APKMALDH1A1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250206884-A1 ULTRAVIOLET RADIATION-CURABLE POLYSILOXANE COMPOSITION, AND DAMPING MATERIAL TAICA CORPORATION (JP) 2025-06-26 US disclosed
CN-118974144-A Ultraviolet-curable polysiloxane composition and damping material 株式会社泰已科 2024-11-15 CN disclosed
WO-2023189433-A1 ULTRAVIOLET RADIATION-CURABLE POLYSILOXANE COMPOSITION, AND DAMPING MATERIAL 株式会社タイカ 2023-10-05 WO disclosed
US-10336697-B2 Spiro[cyclobutane-1,3′-indolin]-2′-one derivatives as bromodomain inhibitors ORION CORPORATION (FI) 2019-07-02 US disclosed
US-10259796-B2 Oxaspiro[2.5]octane derivatives and analogs ZAFGEN, INC. (US) 2019-04-16 US disclosed
US-20180186739-A1 SPIRO[CYCLOBUTANE-1,3'-INDOLIN]-2'-ONE DERIVATIVES AS BROMODOMAIN INHIBITORS ORION CORPORATION (FI) 2018-07-05 US disclosed
US-20180186739-A1 SPIRO[CYCLOBUTANE-1,3'-INDOLIN]-2'-ONE DERIVATIVES AS BROMODOMAIN INHIBITORS ORION CORPORATION (FI) 2018-07-05 US disclosed
EP-2683706-B1 OXASPIRO [2.5]OCTANE DERIVATIVES AND ANALOGS ZAFGEN INC (US) 2018-02-21 EP disclosed
US-20170267634-A1 COMPOUNDS AS CRTH2 ANTAGONIST AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2017-09-21 US disclosed
US-20170196975-A1 CONJUGATES OF AN ANTI-TNF-ALPHA ANTIBODY NEKTAR THERAPEUTICS 2017-07-13 US disclosed
US-7714114-B2 Conjugates of an EPO moiety and a polymer NEKTAR THERAPEUTICS (US) 2010-05-11 US disclosed
US-20100021481-A1 CONJUGATES OF AN ANTI-TNF-ALPHA ANTIBODY NEKTAR THERAPEUTICS (US) 2010-01-28 US disclosed
US-20090280550-A1 Polymer-Factor IX Moiety Conjugates NEKTAR THERAPEUTICS AL, CORPORATION (US) 2009-11-12 US disclosed
US-7579444-B2 Polymer-factor IX moiety conjugates NEKTAR THERAPEUTICS AL, CORPORATION (US) 2009-08-25 US disclosed
US-20080058504-A1 Water soluble polyoxyethylene glylcol polyvinylpyrrolidone, polyvinyl alcohol, polyoxazoline, and/or polyacryloylmorpholine, conjugated to antihemophilic factor NEKTAR THERAPEUTICS 2008-03-06 US disclosed
US-7199223-B2 Water soluble polyoxyethylene glylcol polyvinylpyrrolidone, polyvinyl alcohol, polyoxazoline, and/or polyacryloylmorpholine, conjugated to antihemophilic factor NEKTAR THERAPEUTICS AL, CORPORATION (US) 2007-04-03 US disclosed
US-5755993-A Peroxygen bleach composition activated by piperidone derivatives COLGATE-PALMOLIVE CO. (US) 1998-05-26 US disclosed
WO-1997024429-A9 PEROXYGEN BLEACH COMPOSITION ACTIVATED BY PIPERIDONE DERIVATIVES 1997-09-04 WO disclosed
WO-1997024429-A1 PEROXYGEN BLEACH COMPOSITION ACTIVATED BY PIPERIDONE DERIVATIVES COLGATE-PALMOLIVE COMPANY (US) 1997-07-10 WO disclosed
US-4499100-A CARDIOUVASCULAR DISORDERS SYNTEX (U.S.A.) INC. (US) 1985-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100021481-A1 CONJUGATES OF AN ANTI-TNF-ALPHA ANTIBODY TNF, TNFRSF1A, TNFRSF9 BLM 3468/4885KMT2A 4160/4885PKM 4415/4885
US-20170196975-A1 CONJUGATES OF AN ANTI-TNF-ALPHA ANTIBODY TNF, TNFRSF1A, TNFRSF9 BLM 3656/4885KMT2A 4093/4885PKM 4331/4885
US-10259796-B2 Oxaspiro[2.5]octane derivatives and analogs OXER1, ACOX3, OXGR1 BLM 3094/4885KMT2A 3590/4885PKM 1221/4885
US-20080058504-A1 Water soluble polyoxyethylene glylcol polyvinylpyrrolidone, polyvinyl alcohol, polyoxazoline, and/or polyacryloylmorpholine, conjugated to antihemophilic factor F8, F13A1, F13B BLM 1443/4885KMT2A 1218/4885PKM 1135/4885
US-10336697-B2 Spiro[cyclobutane-1,3′-indolin]-2′-one derivatives as bromodomain inhibitors BRD4, BRD3, BRD1 BLM 1344/4885KMT2A 1425/4885PKM 3639/4885
US-20170267634-A1 COMPOUNDS AS CRTH2 ANTAGONIST AND USES THEREOF HRH2, PTGDR2, HRH1 BLM 4073/4885KMT2A 3790/4885PKM 3146/4885
US-20180186739-A1 SPIRO[CYCLOBUTANE-1,3'-INDOLIN]-2'-ONE DERIVATIVES AS BROMODOMAIN INHIBITORS BRD4, BRD3, BRD1 BLM 1437/4885KMT2A 1501/4885PKM 3650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.