SCHEMBL3276322

SCHEMBL3276322

COc1ccccc1-c1cn([C@H]2[C@@H](O)[C@@H](CO)O[C@@H](SC)[C@@H]2O)nn1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 20/20 0.60
LGALS1 P09382 9/20 0.59
LGALS8 O00214 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3284264 0.86 LGALS3 (0.80) LGALS3LGALS1LGALS8
SCHEMBL3277350 0.84 LGALS3 (0.60) LGALS3LGALS1LGALS8
SCHEMBL23005730 0.83 LGALS3 (0.83) LGALS3LGALS1LGALS8
SCHEMBL16258795 0.83 LGALS3 (0.83) LGALS3LGALS1LGALS8
SCHEMBL13404682 0.83 LGALS3 (0.83) LGALS3LGALS1LGALS8
SCHEMBL13385531 0.83 LGALS3 (0.83) LGALS3LGALS1LGALS8
SCHEMBL3276474 0.83 LGALS3 (0.83) LGALS3LGALS1LGALS8
SCHEMBL3281942 0.82 LGALS3 (0.68) LGALS3LGALS1
SCHEMBL15721140 0.81 LGALS3 (0.62) LGALS3LGALS1LGALS8
SCHEMBL3278177 0.81 LGALS3 (0.62) LGALS3LGALS1LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150320782-A1 Methods, compositions and kits for treating, modulating, or preventing ocular angiogenesis or fibrosis in a subject using a galectin protein inhibitor NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-11-12 US claimed
US-7700763-B2 3-triazolyl-galactoside inhibitors of galectins FORSKARPATENT I SYD AB (SE) 2010-04-20 US claimed
US-20070185041-A1 NOVEL 3-TRIAZOLYL-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (SE) 2007-08-09 US claimed
US-20170095496-A1 GALACTOSIDE INHIBITORS FOR NEW USES GALECTO BIOTECH AB (DK) 2017-04-06 US disclosed
US-20150320782-A1 Methods, compositions and kits for treating, modulating, or preventing ocular angiogenesis or fibrosis in a subject using a galectin protein inhibitor NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-11-12 US disclosed
US-7700763-B2 3-triazolyl-galactoside inhibitors of galectins FORSKARPATENT I SYD AB (SE) 2010-04-20 US disclosed
US-20070185041-A1 NOVEL 3-TRIAZOLYL-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (SE) 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150320782-A1 Methods, compositions and kits for treating, modulating, or preventing ocular angiogenesis or fibrosis in a subject using a galectin protein inhibitor LGALS1, LGALS2, LGALS3BP LGALS3 4/4885LGALS1 1/4885LGALS8 5/4885
US-20170095496-A1 GALACTOSIDE INHIBITORS FOR NEW USES LGALS1, LGALS2, LGALS3 LGALS3 3/4885LGALS1 1/4885LGALS8 5/4885
US-20070185041-A1 NOVEL 3-TRIAZOLYL-GALACTOSIDE INHIBITORS OF GALECTINS LGALS3, LGALS1, LGALS3BP LGALS3 1/4885LGALS1 2/4885LGALS8 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.