⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934717 | 0.84 | — | — | |
| SCHEMBL2696185 | 0.73 | CYP3A4 (0.31) | — | |
| SCHEMBL2699373 | 0.73 | — | — | |
| SCHEMBL2208283 | 0.71 | CYP3A4 (0.30) | — | |
| SCHEMBL10405350 | 0.67 | — | — | |
| SCHEMBL3344254 | 0.66 | ALDH1A1 (0.30) | — | |
| SCHEMBL5831274 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL432350 | 0.64 | — | — | |
| SCHEMBL861711 | 0.64 | ALDH1A1 (0.30) | — | |
| SCHEMBL7729587 | 0.64 | XDH (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173691-B1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | UNIV NORTH CAROLINA STATE (US) | 2013-11-13 | — | — | EP | disclosed |
| US-20130137575-A1 | CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-05-30 | — | — | US | disclosed |
| US-8329954-B2 | Cyclopropene amine compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120035269-A1 | CYCLOPROPENE AMINE COMPOUNDS | SISLER EDWARD C (US) | 2012-02-09 | — | — | US | disclosed |
| US-8093430-B2 | Methods of inhibiting ethylene responses in plants using cyclopropene amine compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-10 | — | — | US | disclosed |
| US-20090124504-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY | 2009-05-14 | — | — | US | disclosed |