Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 6/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 7/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282996 | 0.80 | ADRB1 (0.50) | ADRB1HTR2CHTR2AHTR2BSSTR4 | |
| Hydrochloric Acid SCHEMBL3276614 | 0.79 | ADRB1 (0.49) | ADRB1HTR2CHTR2AHTR2BSSTR4 | |
| SCHEMBL4336202 | 0.79 | ADRB1 (0.49) | ADRB1HTR2CHTR2AHTR2BSSTR4 | |
| Hydrochloric Acid SCHEMBL3276604 | 0.78 | ADRB1 (0.48) | ADRB1HTR2CHTR2AHTR2BSSTR4 | |
| Hydrochloric Acid SCHEMBL3281370 | 0.78 | ADRB1 (0.48) | ADRB1HTR2CHTR2AHTR2BSSTR4 | |
| SCHEMBL21744354 | 0.69 | CD44 (0.46) | HTR2CHTR2AHTR2BHTR6CYP3A4 | |
| Hydrochloric Acid SCHEMBL3276931 | 0.69 | SSTR4 (0.37) | ADRB1HTR2CHTR2AHTR2BSSTR4 | |
| SCHEMBL20565286 | 0.69 | SSTR4 (0.47) | SSTR4 | |
| Hydrochloric Acid SCHEMBL31163412 | 0.69 | CD44 (0.45) | HTR2CHTR2AHTR2BHTR6ALDH1A1 | |
| Bromide SCHEMBL3277525 | 0.68 | HTR2C (0.38) | ADRB1HTR2CHTR2AHTR2BSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123644-B1 | BENZOXAZEPINE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2014-12-17 | — | — | EP | disclosed |
| US-8247403-B2 | Benzoxazepine derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20100087418-A1 | BENZOXAZEPINE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2010-04-08 | — | — | US | disclosed |
| EP-2123644-A1 | BENZOXAZEPINE DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087418-A1 | BENZOXAZEPINE DERIVATIVES AND USE THEREOF | HTR2C, HTR5A, HTR2B | ADRB1 86/4885HTR2C 1/4885PDE3B 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.