Methylamine

Methylamine

SCHEMBL3277347

CN.O=C1C=C(c2ccccc2)C(=O)c2ccccc21

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 5/20 0.89
PTPN1 P18031 5/20 0.63
CDC25B P30305 3/20 0.63
PTPRC P08575 2/20 0.63
PTPRF P10586 1/20 0.63
IDO1 P14902 2/20 0.52
CDC25A P30304 2/20 0.52
ALDH1A1 P00352 2/20 0.52
LMNA P02545 2/20 0.52
MAPT P10636 2/20 0.52
MAPK1 P28482 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MEN1 O00255 1/20 0.52
PLIN1 O60240 1/20 0.52
NR1I2 O75469 1/20 0.52
USP2 O75604 1/20 0.52
GSR P00390 1/20 0.52
TP53 P04637 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29673492 0.94 BACE1 (1.00) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL5485068 0.94 BACE1 (1.00) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL28556962 0.83 BACE1 (0.72) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL11048150 0.83 BACE1 (0.72) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL30433091 0.81 PTPN1 (0.76) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL5139479 0.81 PTPN1 (0.76) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL6555840 0.81 BACE1 (0.75) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL25834756 0.81 BACE1 (0.75) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL13020950 0.79 BACE1 (0.72) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL31423340 0.79 BACE1 (1.00) BACE1PTPN1CDC25BPTPRCPTPRF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090262623-A1 OPTICAL MEDIA FORMAT FLEXPLAY TECHNOLOGIES, INC. (US) 2009-10-22 US claimed
EP-1817771-A2 OPTICAL MEDIA, READ INHIBITING AGENTS, AND METHODS OF MAKING AND USING SAME Flexplay Technologies, Inc. (US) 2007-08-15 EP claimed
US-20060136958-A1 Optical media, read inhibiting agents and methods of making and using same FLEXPLAY TECHNOLOGIES, INC. (US) 2006-06-22 US claimed
US-20060126484-A1 Optical media, read inhibiting agents and methods of making and using same FLEXPLAY TECHNOLOGIES, INC. (US) 2006-06-15 US claimed
WO-2006053330-A2 OPTICAL MEDIA, READ INHIBITING AGENTS, AND METHODS OF MAKING AND USING SAME FLEXPLAY TECHNOLOGIES, INC. (US) 2006-05-18 WO claimed
US-20060105134-A1 Optical media, read inhibiting agents and methods of making and using same FLEXPLAY TECHNOLOGIES, INC. (US) 2006-05-18 US claimed
US-7698716-B2 Optical media, read inhibiting agents and methods of making and using same FLEXPLAY TECHNOLOGIES, INC. (US) 2010-04-13 US disclosed
US-20090262623-A1 OPTICAL MEDIA FORMAT FLEXPLAY TECHNOLOGIES, INC. (US) 2009-10-22 US disclosed
CN-101099204-A Optical media, read inhibiting agents and methods of making and using same FLEXPLAY TECHNOLOGIES INC (US) 2008-01-02 CN disclosed
EP-1817771-A2 OPTICAL MEDIA, READ INHIBITING AGENTS, AND METHODS OF MAKING AND USING SAME Flexplay Technologies, Inc. (US) 2007-08-15 EP disclosed
US-20060136948-A1 Optical media, read inhibiting agents and methods of making and using same FLEXPLAY TECHNOLOGIES, INC. (US) 2006-06-22 US disclosed
US-20060136947-A1 Optical media, read inhibiting agents and methods of making and using same FLEXPLAY TECHNOLOGIES, INC. (US) 2006-06-22 US disclosed
US-20060136958-A1 Optical media, read inhibiting agents and methods of making and using same FLEXPLAY TECHNOLOGIES, INC. (US) 2006-06-22 US disclosed
US-20060126484-A1 Optical media, read inhibiting agents and methods of making and using same FLEXPLAY TECHNOLOGIES, INC. (US) 2006-06-15 US disclosed
WO-2006053330-A2 OPTICAL MEDIA, READ INHIBITING AGENTS, AND METHODS OF MAKING AND USING SAME FLEXPLAY TECHNOLOGIES, INC. (US) 2006-05-18 WO disclosed
US-20060105134-A1 Optical media, read inhibiting agents and methods of making and using same FLEXPLAY TECHNOLOGIES, INC. (US) 2006-05-18 US disclosed