Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.75 |
| ▸ | CDC25B | P30305 | 5/20 | 0.60 |
| ▸ | IDO1 | P14902 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CDC25A | P30304 | 2/20 | 0.60 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.60 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | SNCA | P37840 | 2/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596446 | 0.91 | PTPN1 (0.64) | BACE1CDC25BIDO1MEN1KMT2A | |
| SCHEMBL5485068 | 0.86 | BACE1 (1.00) | BACE1CDC25BIDO1MEN1KMT2A | |
| SCHEMBL29673492 | 0.86 | BACE1 (1.00) | BACE1CDC25BIDO1MEN1KMT2A | |
| SCHEMBL9286666 | 0.83 | BACE1 (0.60) | BACE1CDC25BIDO1MEN1KMT2A | |
| SCHEMBL1708066 | 0.83 | BACE1 (0.60) | BACE1CDC25BIDO1MEN1KMT2A | |
| SCHEMBL28564373 | 0.83 | BACE1 (0.60) | BACE1CDC25BIDO1MEN1KMT2A | |
| SCHEMBL7605733 | 0.83 | BACE1 (0.60) | BACE1CDC25BIDO1MEN1KMT2A | |
| Methylamine SCHEMBL3277347 | 0.81 | BACE1 (0.89) | BACE1CDC25BIDO1MEN1KMT2A | |
| SCHEMBL312389 | 0.80 | BACE1 (1.00) | BACE1CDC25BIDO1MEN1KMT2A | |
| SCHEMBL8598269 | 0.80 | BACE1 (0.59) | BACE1CDC25BIDO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335777-A | Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus | 三菱化学株式会社 | 2022-11-11 | — | — | CN | claimed |
| US-6835755-B1 | Naphthoquinone derivatives and their use in the treatment and control of tuberculosis | UNIVERSITY OF PRETORIA (ZA) | 2004-12-28 | — | — | US | claimed |
| EP-1194137-A2 | NAPHTHOQUINONE DERIVATIVES AND THEIR USE IN THE TREATMENT AND CONTROL OF TUBERCULOSIS | University of Pretoria (ZA) | 2002-04-10 | — | — | EP | claimed |
| WO-2001000554-A2 | NAPHTHOQUINONE DERIVATIVES AND THEIR USE IN THE TREATMENT AND CONTROL OF TUBERCULOSIS | UNIVERSITY OF PRETORIA (ZA) | 2001-01-04 | — | — | WO | claimed |
| EP-0653441-B1 | Polymer scale preventive agent | SHINETSU CHEMICAL CO (JP) | 1998-02-04 | — | — | EP | claimed |
| EP-0653441-A1 | Polymer scale preventive agent | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-05-17 | — | — | EP | claimed |
| CN-116507975-A | Electrophotographic photoreceptor, cartridge using the same, and image forming apparatus | 三菱化学株式会社 | 2023-07-28 | — | — | CN | disclosed |
| CN-116406455-A | Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus | 三菱化学株式会社 | 2023-07-07 | — | — | CN | disclosed |
| CN-115335777-A | Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus | 三菱化学株式会社 | 2022-11-11 | — | — | CN | disclosed |
| US-20200283417-A1 | AZIRIDINYL AND AMINO DIMERIC NAPHTHOQUINONE COMPOUNDS AND USE FOR ACUTE MYELOID LEUKEMIA | UNIVERSITY OF MARYLAND, BALTIMORE | 2020-09-10 | — | — | US | disclosed |
| CN-105911822-B | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士施乐株式会社 | 2019-12-06 | — | — | CN | disclosed |
| WO-2018067842-A1 | AZIRIDINYL AND AMINO DIMERIC NAPHTHOQUINONE COMPOUNDS AND USE FOR ACUTE MYELOID LEUKEMIA | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2018-04-12 | — | — | WO | disclosed |
| EP-1194137-B1 | NAPHTHOQUINONE DERIVATIVES AND THEIR USE IN THE TREATMENT AND CONTROL OF TUBERCULOSIS | UNIV PRETORIA (ZA) | 2004-12-29 | — | — | EP | disclosed |
| US-6835755-B1 | Naphthoquinone derivatives and their use in the treatment and control of tuberculosis | UNIVERSITY OF PRETORIA (ZA) | 2004-12-28 | — | — | US | disclosed |
| EP-1194137-A2 | NAPHTHOQUINONE DERIVATIVES AND THEIR USE IN THE TREATMENT AND CONTROL OF TUBERCULOSIS | University of Pretoria (ZA) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001000554-A2 | NAPHTHOQUINONE DERIVATIVES AND THEIR USE IN THE TREATMENT AND CONTROL OF TUBERCULOSIS | UNIVERSITY OF PRETORIA (ZA) | 2001-01-04 | — | — | WO | disclosed |
| EP-0653441-B1 | Polymer scale preventive agent | SHINETSU CHEMICAL CO (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5492982-A | MIXTURE OF NAPHTHOQUINONE DIMER, WATER SOLUBLE POLYMER AND AN INORGANIC COLLOID | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-20 | — | — | US | disclosed |
| EP-0653441-A1 | Polymer scale preventive agent | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |
| US-5292873-A | Nucleic acids labeled with naphthoquinone probe | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283417-A1 | AZIRIDINYL AND AMINO DIMERIC NAPHTHOQUINONE COMPOUNDS AND USE FOR ACUTE MYELOID LEUKEMIA | MCL1, NPM1, ABL1 | BACE1 4773/4885CDC25B 502/4885IDO1 494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.