SCHEMBL3277882

SCHEMBL3277882

C=C(c1nc2ccccc2o1)c1nc2ccccc2o1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 2/20 0.50
MAPT P10636 9/20 0.48
NPC1 O15118 5/20 0.48
RAB9A P51151 5/20 0.48
KDM4E B2RXH2 6/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPK1 P28482 2/20 0.46
PSMB8 P28062 1/20 0.46
ALDH1A1 P00352 5/20 0.45
HTT P42858 3/20 0.45
FAAH O00519 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
CES1 P23141 1/20 0.45
DAGLA Q9Y4D2 1/20 0.45
NPSR1 Q6W5P4 3/20 0.44
LMNA P02545 2/20 0.44
TP53 P04637 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
HPGD P15428 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12545534 0.89 XDH (0.50) XDHMAPTNPC1RAB9AKDM4E
SCHEMBL23207495 0.88 XDH (0.50) XDHMAPTNPC1RAB9AKDM4E
SCHEMBL4464221 0.84 XDH (0.49) XDHMAPTNPC1RAB9AKDM4E
SCHEMBL29805838 0.84 XDH (0.49) XDHMAPTNPC1RAB9AKDM4E
SCHEMBL23208040 0.81 MAPT (0.46) XDHMAPTNPC1RAB9AKDM4E
SCHEMBL17951858 0.81 FAAH (0.54) XDHMAPTNPC1RAB9AKDM4E
SCHEMBL6630546 0.80 FAAH (0.50) XDHMAPTNPC1RAB9AKDM4E
SCHEMBL6662363 0.80 FAAH (0.50) XDHMAPTNPC1RAB9AKDM4E
SCHEMBL23902532 0.79 XDH (0.51) XDHMAPTNPC1RAB9AKDM4E
SCHEMBL8032979 0.79 XDH (0.54) XDHMAPTNPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0030917-B2 OPTICAL BRIGHTENERS FROM BISTYRYL BENZENE, PROCESS FOR THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1991-03-20 EP claimed
US-4778623-A Fluorescent brighteners consisting of bis-styrylbenzene compounds, a process for their preparation and their use CIBA-GEIGY CORPORATION (US) 1988-10-18 US claimed
EP-0030917-B1 OPTICAL BRIGHTENERS FROM BISTYRYL BENZENE, PROCESS FOR THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1985-01-23 EP claimed
EP-0030917-A2 Optical brighteners from bistyryl benzene, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-06-24 EP claimed
JP-11048665-A None JP disclosed
CN-111269355-A Polymer containing heterocyclic structure and application thereof 深圳市康益保健用品有限公司 2020-06-12 CN disclosed
US-8545008-B2 Recording medium CANON KABUSHIKI KAISHA (JP) 2013-10-01 US disclosed
EP-2392468-B1 Recording medium CANON KK (JP) 2013-07-17 EP disclosed
US-8247042-B2 Recording medium CANON KABUSHIKI KAISHA (JP) 2012-08-21 US disclosed
EP-2392469-B1 Recording medium CANON KK (JP) 2012-07-18 EP disclosed
US-8198213-B2 Thermal transfer image receiving sheet and production method of the same DAI NIPPON PRINTING CO., LTD. (JP) 2012-06-12 US disclosed
EP-2392469-A1 Recording medium Canon Kabushiki Kaisha (JP) 2011-12-07 EP disclosed
EP-0064030-A1 Dyeing auxiliary mixture and its use in dyeing synthetic fibrous materials CIBA-GEIGY AG (CH) 1982-11-03 EP disclosed
EP-0058880-A1 Mixtures of optical brighteners HOECHST AKTIENGESELLSCHAFT (DE) 1982-09-01 EP disclosed
EP-0058637-A1 Stable preparation of a treatment product for a textile substrate CIBA-GEIGY AG (CH) 1982-08-25 EP disclosed
US-4294711-A STILBENE OPTICAL BRIGHTENERS AND SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1981-10-13 US disclosed
EP-0030917-A2 Optical brighteners from bistyryl benzene, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-06-24 EP disclosed
US-4196229-A NITRILES, ESTERS, AMIDES, SULFONES, AND KETONES SANDOZ LTD. (CH) 1980-04-01 US disclosed
US-4145480-A POLYOLEFIN RESIN, TITANIUM DIOXIDE MITSUBISHI PAPER MILLS, LTD. (JP) 1979-03-20 US disclosed
US-4108887-A Divinyl stilbenes as optical brighteners SANDOZ LTD. (CH) 1978-08-22 US disclosed