Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27638604 | 0.83 | — | — | |
| SCHEMBL27524556 | 0.77 | — | — | |
| SCHEMBL12039277 | 0.74 | — | — | |
| SCHEMBL12665760 | 0.74 | — | — | |
| SCHEMBL17861575 | 0.74 | — | — | |
| SCHEMBL12989432 | 0.74 | — | — | |
| SCHEMBL11624177 | 0.74 | — | — | |
| SCHEMBL21865053 | 0.74 | — | — | |
| SCHEMBL21865019 | 0.74 | — | — | |
| SCHEMBL22275454 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696349-B2 | Method for asymmetric synthesis | BASF SE (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20090326226-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 2009-12-31 | — | — | US | disclosed |
| EP-1689760-B1 | METHOD FOR ASYMMETRIC SYNTHESIS | BASF SE (DE) | 2009-10-28 | — | — | EP | disclosed |
| US-20090227801-A1 | LIGANDS FOR USE IN ASYMMETRIC HYDROFORMYLATION | BASF AKTIENGESELLSCHAFT (DE) | 2009-09-10 | — | — | US | disclosed |
| US-7442842-B2 | Method for asymmetric synthesis | BASF SE (DE) | 2008-10-28 | — | — | US | disclosed |
| US-20070073092-A1 | Method for asymmetric synthesis | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073092-A1 | Method for asymmetric synthesis | COASY, PIN1, INF2 | PDK1 2641/4885 |
| US-20090227801-A1 | LIGANDS FOR USE IN ASYMMETRIC HYDROFORMYLATION | PFKFB3, PHPT1, PFKFB4 | PDK1 1312/4885 |
| US-20090326226-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | COASY, PIN1, INF2 | PDK1 2641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.