⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11033735 | 0.81 | KMT2A (0.44) | — | |
| SCHEMBL6671760 | 0.77 | — | — | |
| SCHEMBL16310738 | 0.74 | KDM4E (0.44) | — | |
| SCHEMBL3278611 | 0.73 | — | — | |
| SCHEMBL12189389 | 0.73 | — | — | |
| SCHEMBL2608518 | 0.73 | — | — | |
| SCHEMBL3278056 | 0.73 | — | — | |
| SCHEMBL2605756 | 0.73 | — | — | |
| SCHEMBL3285821 | 0.73 | KDM4E (0.39) | — | |
| SCHEMBL19513164 | 0.72 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297403-B1 | OXIDATION OF A (DI)ARYL METHANE OR METHYLENE DERIVATIVE IN PRESENCE OF AN AMINE OXIDE OR HYDROXYAMINE DERIVATIVE MEDIATOR; BY-PRODUCT INHIBITION | Consortium für elektrochemische Industrie GmbH (DE) | 2001-10-02 | — | — | US | claimed |
| US-6169213-B1 | REACTING A HETEROARYL METHANOL WITH AN OXIDANT AND A MEDIATOR CONTAINING AMINO OXIDE GROUP TO FORM HETEROARYL ALDEHYDE OR A HETEROARYL KETONE | Consortium f{umlaut over (u)}r elektrochemische Industrie GmbH (DE) | 2001-01-02 | — | — | US | claimed |
| EP-0913382-B1 | Process for the preparation of aldehydes and ketones | CONSORTIUM ELEKTROCHEM IND (DE) | 2000-11-08 | — | — | EP | claimed |
| EP-0943032-B1 | MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN OR LIGNIN-CONTAINING MATERIALS, AND PROCESS FOR USING THE SAME | CONSORTIUM ELEKTROCHEM IND (DE) | 2000-09-13 | — | — | EP | claimed |
| US-6069282-A | REACTION OF VINYL-, ALKYNYL- OR ARYL-METHANOLS WITH THE AID OF A MEDIATOR AND AN OXIDANT, WHEREIN THE MEDIATOR IS SELECTED FROM THE GROUP OF THE ALIPHATIC, CYCLOALIPHATIC, HETEROCYCLIC OR AROMATIC NO OR NOH CONTAINING COMPOUNDS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2000-05-30 | — | — | US | claimed |
| US-6023000-A | Process for the preparation of aldehydes and ketones | Consortium fur elektrochemisch Industrie GmbH (DE) | 2000-02-08 | — | — | US | claimed |
| CN-1240008-A | Multicomponent system for modifying, degrading or bleaching lignin, lignin-containing materials or the like and method for the use thereof | ELEKTOCHEMISCHE IND GMBH (DE) | 1999-12-29 | — | — | CN | claimed |
| EP-0943032-A1 | MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES, AND PROCESS FOR USING THE SAME | Consortium für elektrochemische Industrie GmbH (DE) | 1999-09-22 | — | — | EP | claimed |
| EP-0913382-A1 | Process for the preparation of aldehydes and ketones | Consortium für elektrochemische Industrie GmbH (DE) | 1999-05-06 | — | — | EP | claimed |
| WO-1998026127-A1 | MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES, AND PROCESS FOR USING THE SAME | Consortium für elektrochemische Industrie GmbH (DE) | 1998-06-18 | — | — | WO | claimed |
| US-10544161-B2 | Anti-fibrotic pyridinones | INTERMUNE, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-20190144467-A1 | ANTI-FIBROTIC PYRIDINONES | GENENTECH, INC. | 2019-05-16 | — | — | US | disclosed |
| US-10233195-B2 | Anti-fibrotic pyridinones | INTERMUNE, INC. (US) | 2019-03-19 | — | — | US | disclosed |
| US-20170121345-A1 | ANTI-FIBROTIC PYRIDINONES | GENENTECH, INC. | 2017-05-04 | — | — | US | disclosed |
| US-8039486-B2 | Viricides, immunomodulators or HIV entry inhibitors; lymphadenopathy associated virus, human T-cell leukemia/lymphoma virus; AIDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-10-18 | — | — | US | disclosed |
| EP-0885868-A1 | Oxidation-process for the production of aldehydes and ketones in the presence of nitrogen-containing compounds | Consortium für elektrochemische Industrie GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0882814-A1 | System and process for the electrochemical cleavage of compounds | Consortium für elektrochemische Industrie GmbH (DE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1998026127-A1 | MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES, AND PROCESS FOR USING THE SAME | Consortium für elektrochemische Industrie GmbH (DE) | 1998-06-18 | — | — | WO | disclosed |
| US-4831142-A | Spiro indoline-pyranobenzoxazinones | PPG INDUSTRIES, INC. (US) | 1989-05-16 | — | — | US | disclosed |
| US-4785097-A | Method for synthesizing spiro-oxazines | PPG INDUSTRIES, INC. (US) | 1988-11-15 | — | — | US | disclosed |