SCHEMBL11033735

SCHEMBL11033735

Oc1ncccc1N=Nc1cccnc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 11/20 0.44
MEN1 O00255 10/20 0.44
MAPT P10636 9/20 0.44
HTT P42858 6/20 0.44
SMN1; SMN2 Q16637 6/20 0.44
KDM4E B2RXH2 6/20 0.44
LMNA P02545 5/20 0.44
NPC1 O15118 4/20 0.44
L3MBTL1 Q9Y468 6/20 0.42
TDP1 Q9NUW8 6/20 0.42
MAPK1 P28482 4/20 0.42
OPRK1 P41145 3/20 0.42
GLO1 Q04760 2/20 0.41
HSP90AA1 P07900 3/20 0.39
NSD2 O96028 2/20 0.39
TNF P01375 1/20 0.39
CXCL8 P10145 1/20 0.39
PAX8 Q06710 1/20 0.39
KLF5 Q13887 1/20 0.39
CASP6 P55212 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11146612 0.82 MEN1 (0.33) KMT2AMEN1MAPTHTTSMN1; SMN2
SCHEMBL11146614 0.82 MEN1 (0.33) KMT2AMEN1MAPTHTTSMN1; SMN2
SCHEMBL6671760 0.81
SCHEMBL3278213 0.81
SCHEMBL19513164 0.80 ALDH1A1 (0.36) KMT2AMEN1MAPTHTTSMN1; SMN2
SCHEMBL11495779 0.75 LMNA (0.36) KMT2AMAPTHTTSMN1; SMN2KDM4E
SCHEMBL11495776 0.75 LMNA (0.36) KMT2AMAPTHTTSMN1; SMN2KDM4E
SCHEMBL103661 0.70
SCHEMBL2592408 0.70 TDP1 (0.44) KMT2AMEN1MAPTHTTSMN1; SMN2
SCHEMBL29366238 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0009989-B1 PHOTOGRAPHIC RECORDING MATERIAL CONTAINING BLOCKED PHOTOGRAPHICALLY USEFUL COMPOUND EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-01-23 EP disclosed
US-4358525-A STORAGE STABLE COLOR FILMS FOR DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1982-11-09 US disclosed
US-4310612-A NUCLEOPHILIC DISPLACEMENT EASTMAN KODAK COMPANY (US) 1982-01-12 US disclosed
EP-0009989-A2 Photographic recording material containing blocked photographically useful compound EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-04-16 EP disclosed