SCHEMBL3278635

SCHEMBL3278635

COc1ccc(CN(C=Cc2ccccc2)Cc2ccc(OC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.58
RAB9A P51151 2/20 0.51
G6PC1 P35575 1/20 0.50
TRPM8 Q7Z2W7 1/20 0.49
LTA4H P09960 1/20 0.49
ACHE P22303 2/20 0.47
SNCA P37840 1/20 0.47
BCHE P06276 1/20 0.47
OPRM1 P35372 1/20 0.47
OPRL1 P41146 1/20 0.47
ALDH1A1 P00352 2/20 0.45
MAOB P27338 2/20 0.45
PPARG P37231 1/20 0.45
NFE2L2 Q16236 1/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
HSPD1 P10809 1/20 0.45
TNFRSF1A P19438 1/20 0.45
HSPE1 P61604 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10628598 0.80 TSHR (0.44) G6PC1TRPM8ALDH1A1MAOBTSHR
SCHEMBL5752214 0.77 KCNH2 (0.62) TRPA1RAB9AACHEBCHE
SCHEMBL5752211 0.77 KCNH2 (0.62) TRPA1RAB9AACHEBCHE
SCHEMBL9441407 0.77 MEN1 (0.46) TRPA1RAB9AG6PC1TRPM8ACHE
SCHEMBL9441414 0.77 MEN1 (0.46) TRPA1RAB9AG6PC1TRPM8ACHE
SCHEMBL31190146 0.76 TRPM8 (0.54) TRPA1G6PC1TRPM8ACHESNCA
SCHEMBL15105021 0.75 TRPA1 (0.63) TRPA1RAB9ALTA4HALDH1A1MAOB
SCHEMBL3278627 0.75 TRPA1 (0.63) TRPA1RAB9ATRPM8BCHEALDH1A1
SCHEMBL3869325 0.75 TRPA1 (0.63) TRPA1RAB9ALTA4HALDH1A1MAOB
SCHEMBL8845585 0.74 TRPA1 (1.00) TRPA1RAB9AALDH1A1NFE2L2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700248-B2 Organic charge transporting polymers including charge transport moieties and silane groups, and silsesquioxane compositions prepared therefrom EASTMAN KODAK COMPANY (US) 2010-04-20 US disclosed
EP-1380596-B1 Organic charge transporting polymers including charge transport mojeties and silane groups, and silsesquioxane compositions prepared therefrom EASTMAN KODAK CO (US) 2007-12-05 EP disclosed
US-20040126683-A1 Organic charge transporting polymers including charge transport moieties and silane groups, and silsesquioxane compositions prepared therefrom CITICORP NORTH AMERICA, INC., AS AGENT 2004-07-01 US disclosed
EP-1380596-A1 Organic charge transporting polymers including charge transport mojeties and silane groups, and silsesquioxane compositions prepared therefrom Heidelberger Druckmaschinen Aktiengesellschaft (DE) 2004-01-14 EP disclosed