Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278647 | 1.00 | PTGS1 (0.49) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL11285019 | 0.82 | L3MBTL1 (0.45) | LMNACYP2C9AKR1C3TSHRAKR1C2 | |
| SCHEMBL13631877 | 0.80 | HDAC8 (0.32) | PTGS1LMNACYP2C9ESR1CHRM1 | |
| SCHEMBL7623081 | 0.80 | TYR (0.50) | LMNACYP2C9 | |
| SCHEMBL1178318 | 0.79 | PTGS1 (0.53) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL1649474 | 0.79 | PTGS1 (0.53) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL2919840 | 0.79 | PTGS1 (0.53) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL27843929 | 0.77 | MEN1 (0.46) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL28245936 | 0.77 | TYR (0.47) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL29047003 | 0.76 | SRD5A2 (0.39) | LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102336714-A | Hydantoin ibuprofen derivative and synthetic method and application thereof | UNIV JILIN | 2012-02-01 | — | — | CN | claimed |
| CN-102066316-A | Novel compounds derived from taurine, process for their preparation and pharmaceutical compositions containing them | EMS SA | 2011-05-18 | — | — | CN | claimed |
| EP-0766658-B1 | PROCESS FOR IMPROVING ENANTIOMERIC PURITY OF ALDEHYDES | UNION CARBIDE CHEM PLASTIC (US) | 2002-04-10 | — | — | EP | claimed |
| EP-0862549-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS | UNION CARBIDE CHEM PLASTIC (US) | 2000-05-31 | — | — | EP | claimed |
| JP-2966094-B2 | — | — | 1999-10-25 | — | — | JP | claimed |
| EP-0862549-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-09-09 | — | — | EP | claimed |
| US-5739385-A | OXIDIZING AN OPTICALLY ACTIVE ALDEHYDE WITH A PERACID IN THE PRESENCE OF AN AMINE AND/OR AMINE N-OXIDE CATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-04-14 | — | — | US | claimed |
| EP-0673381-A4 | HOMOGENEOUS BIMETALLIC HYDROFORMYLATION CATALYSTS AND PROCESSES UTILIZING THESE CATALYSTS FOR CONDUCTING HYDROFORMYLATION REACTIONS. | UNIV LOUISIANA STATE (US) | 1997-09-10 | — | — | EP | claimed |
| WO-1997014669-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-04-24 | — | — | WO | claimed |
| EP-0766658-A1 | PROCESS FOR IMPROVING ENANTIOMERIC PURITY OF ALDEHYDES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-04-09 | — | — | EP | claimed |
| US-5491266-A | REACTING CHIRAL COMPOUND IN PRESENCE OF OPTICALLY ACTIVE METAL-LIGAND COMPLEX | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-02-13 | — | — | US | claimed |
| EP-0600020-B1 | ASYMMETRIC SYNTHESES | UNION CARBIDE CHEM PLASTIC (US) | 1996-01-31 | — | — | EP | claimed |
| WO-1996000200-A1 | PROCESS FOR IMPROVING ENANTIOMERIC PURITY OF ALDEHYDES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-01-04 | — | — | WO | claimed |
| EP-0673381-A1 | HOMOGENEOUS BIMETALLIC HYDROFORMYLATION CATALYSTS AND PROCESSES UTILIZING THESE CATALYSTS FOR CONDUCTING HYDROFORMYLATION REACTIONS | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 1995-09-27 | — | — | EP | claimed |
| US-5430194-A | Maintaining solution at temperature above eutectic temperature of mixture such that solubility limit of first aldehyde is exceeded to form crystalline first aldehyde containing less of second aldehyde | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-07-04 | — | — | US | claimed |
| WO-1994020510-A1 | HOMOGENEOUS BIMETALLIC HYDROFORMYLATION CATALYSTS AND PROCESSES UTILIZING THESE CATALYSTS FOR CONDUCTING HYDROFORMYLATION REACTIONS | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 1994-09-15 | — | — | WO | claimed |
| WO-1993003839-A1 | ASYMMETRIC SYNTHESES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-03-04 | — | — | WO | claimed |
| CN-102336714-A | Hydantoin ibuprofen derivative and synthetic method and application thereof | UNIV JILIN | 2012-02-01 | — | — | CN | disclosed |
| US-20070073092-A1 | Method for asymmetric synthesis | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-29 | — | — | US | disclosed |
| EP-0600020-B1 | ASYMMETRIC SYNTHESES | UNION CARBIDE CHEM PLASTIC (US) | 1996-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073092-A1 | Method for asymmetric synthesis | COASY, PIN1, INF2 | PTGS1 2977/4885PTGS2 1491/4885ALOX5 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.