Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.68 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679054 | 1.00 | DNM1 (0.68) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL672858 | 1.00 | DNM1 (0.68) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL16265487 | 1.00 | DNM1 (0.68) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL10426271 | 1.00 | DNM1 (0.68) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8158097 | 1.00 | DNM1 (0.68) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8980572 | 1.00 | DNM1 (0.68) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL10479136 | 1.00 | DNM1 (0.68) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL7610794 | 1.00 | DNM1 (0.68) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL6560896 | 1.00 | DNM1 (0.68) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL1673890 | 1.00 | DNM1 (0.68) | DNM1TSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691896-B2 | Analogs of salinosporamide A | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-04-06 | — | — | US | disclosed |
| EP-1931679-A4 | ANALOGS OF SALINOSPORAMIDE A | HARVARD COLLEGE (US) | 2009-07-29 | — | — | EP | disclosed |
| US-20090054665-A1 | ANALOGS OF SALINOSPORAMIDE A | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-02-26 | — | — | US | disclosed |
| EP-1931679-A1 | ANALOGS OF SALINOSPORAMIDE A | The President and Fellows of Harvard College (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007021897-A1 | ANALOGS OF SALINOSPORAMIDE A | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-02-22 | — | — | WO | disclosed |
| US-5646098-A | Carbonyl containing compounds and their derivatives as multi-functional fuel and lube additives | EXXON CHEMICAL PATENTS INC (US) | 1997-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054665-A1 | ANALOGS OF SALINOSPORAMIDE A | PSME1, PSMG3, PSMD5 | DNM1 3528/4885TSHR 3963/4885MEN1 2671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.