SCHEMBL3279428

SCHEMBL3279428

CCC(=CC=CC(=O)O)c1cccc(CCc2ccc(C(O[SiH](C)C)C(C)(C)C)c(C(O[SiH](C)C)C(C)(C)C)c2)c1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
VDR P11473 5/20 0.40
PTAFR P25105 1/20 0.30
CYP26A1 O43174 1/20 0.30
CYP26B1 Q9NR63 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6884303 0.89 SLC7A5 (0.32) CYP26A1CYP26B1
SCHEMBL3278879 0.88 VDR (0.39) VDR
SCHEMBL3280033 0.85 VDR (0.38) VDR
SCHEMBL6888198 0.84 DAO (0.31)
SCHEMBL3280701 0.84 VDR (0.60) VDR
SCHEMBL3279904 0.83 VDR (0.37) VDR
SCHEMBL3279984 0.82 CYP4F2 (0.34)
SCHEMBL3279353 0.81 VDR (0.34) VDR
SCHEMBL3279361 0.81 VDR (0.34) VDR
SCHEMBL6886723 0.80 MAOB (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700657-B2 Vitamin D analogs GALDERMA RESEARCH & DEVELOPMENT (FR) 2010-04-20 US disclosed