SCHEMBL3279904

SCHEMBL3279904

CCC(=CCO)c1cccc(CCc2ccc(C(O[SiH](C)C)C(C)(C)C)c(C(O[SiH](C)C)C(C)(C)C)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
VDR P11473 2/20 0.37
CYP4F2 P78329 2/20 0.30
CYP4A11 Q02928 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3278879 0.87 VDR (0.39) VDR
SCHEMBL3279353 0.86 VDR (0.34) VDR
SCHEMBL3279361 0.86 VDR (0.34) VDR
SCHEMBL3280033 0.86 VDR (0.38) VDR
SCHEMBL3279984 0.83 CYP4F2 (0.34) CYP4F2CYP4A11
SCHEMBL3279428 0.83 VDR (0.40) VDR
SCHEMBL6890580 0.82
SCHEMBL3280701 0.81 VDR (0.60) VDR
SCHEMBL3280281 0.81 VDR (0.38) VDR
SCHEMBL6886723 0.81 MAOB (0.37) CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700657-B2 Vitamin D analogs GALDERMA RESEARCH & DEVELOPMENT (FR) 2010-04-20 US disclosed
US-20040224929-A1 Novel vitamin D analogs GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2004-11-11 US disclosed