Sugi Predict

Sugi Predict / Compounds / SCHEMBL3279705

SCHEMBL3279705

SCHEMBL3279705

COC(=O)C(=NO)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ TET2 Q6N021 1/20 0.33
▸ EGLN1 Q9GZT9 1/20 0.33
▸ POLB P06746 1/20 0.32
▸ CASP6 P55212 1/20 0.32
▸ TSHR P16473 2/20 0.32
▸ KEAP1 Q14145 1/20 0.32
▸ NFE2L2 Q16236 1/20 0.32
▸ HCAR2 Q8TDS4 1/20 0.32
▸ THRB P10828 1/20 0.32
▸ BLM P54132 1/20 0.32
▸ PMP22 Q01453 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17282357 0.86 ALDH1A1 (0.36) ALDH1A1TDP1KDM4ETET2EGLN1
SCHEMBL4962432 0.86 ALDH1A1 (0.42) ALDH1A1TDP1KDM4ETET2EGLN1
SCHEMBL4962427 0.86 ALDH1A1 (0.42) ALDH1A1TDP1KDM4ETET2EGLN1
SCHEMBL17279082 0.86 ALDH1A1 (0.42) ALDH1A1TDP1KDM4ETET2EGLN1
SCHEMBL7948916 0.84 KDM4E (0.36) ALDH1A1TDP1KDM4E
SCHEMBL18393174 0.83 MAPT (0.42) ALDH1A1EGLN1TSHRNPSR1CYP2D6
SCHEMBL22774906 0.80 ALDH1A1 (0.32) ALDH1A1TDP1KDM4ETET2EGLN1
SCHEMBL22213919 0.80 ALDH1A1 (0.32) ALDH1A1TDP1KDM4ETET2EGLN1
SCHEMBL18891139 0.80 ALDH1A1 (0.32) ALDH1A1TDP1KDM4ETET2EGLN1
SCHEMBL5433710 0.78 MGAM (0.41) ALDH1A1TDP1KDM4ETET2EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112552504-A Synthesis method of epoxysuccinic acid-2- (hydroxyimino) sodium malonate copolymer 山东泰和水处理科技股份有限公司 2021-03-26 — — CN claimed
CN-112538161-A Preparation method of epoxysuccinic acid-2- (hydroxyimino) sodium malonate copolymer 山东泰和水处理科技股份有限公司 2021-03-23 — — CN claimed
US-10060033-B2 Precursors for the production of thin oxide layers and the use thereof MERCK PATENT GMBH (DE) 2018-08-28 — — US claimed
EP-3041847-B1 PRECURSORS FOR THE PRODUCTION OF THIN OXIDE LAYERS AND THE USE THEREOF MERCK PATENT GMBH (DE) 2017-09-27 — — EP claimed
US-20160208386-A1 PRECURSORS FOR THE PRODUCTION OF THIN OXIDE LAYERS AND THE USE THEREOF MERCK PATENT GMBH (DE) 2016-07-21 — — US claimed
US-20250188066-A1 ANTIVIRAL 1,3-DI-OXO-INDENE COMPOUNDS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2025-06-12 — — US disclosed
US-12286423-B2 Antiviral 1,3-di-oxo-indene compounds NOVARTIS AG (CH) 2025-04-29 — — US disclosed
EP-3898587-B1 CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS UNIV FREIBURG ALBERT LUDWIGS (DE) 2024-06-26 — — EP disclosed
EP-3898587-B1 CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS UNIV FREIBURG ALBERT LUDWIGS (DE) 2024-06-26 — — EP disclosed
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents WILLIAM MARSH RICE UNIVERSITY (US) 2023-09-26 — — US disclosed
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents WILLIAM MARSH RICE UNIVERSITY (US) 2023-09-26 — — US disclosed
CN-115867545-A Antiviral 1,3 dioxoindene compounds 诺华股份有限公司 2023-03-28 — — CN disclosed
EP-0845026-A1 MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES CALL, Hans-Peter Dr. (DE) 1998-06-03 — — EP disclosed
WO-1997048786-A1 MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES CALL HANS PETER (DE) 1997-12-24 — — WO disclosed
EP-0811602-A1 Process for the preparation of salts of the aminomalonic ester HÜLS AKTIENGESELLSCHAFT (DE) 1997-12-10 — — EP disclosed
EP-0811607-A1 Process for the nitrosation of C-H- acid compounds HÜLS AKTIENGESELLSCHAFT (DE) 1997-12-10 — — EP disclosed
WO-1997036039-A1 A MULTICOMPONENT SYSTEM FOR CHANGING, DEGRADING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES AND PROCESSES FOR ITS USE Consortium für elektrochemische Industrie GmbH (DE) 1997-10-02 — — WO disclosed
EP-0517041-A1 New Cephem Compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-12-09 — — EP disclosed
US-4918067-A Heterocyclic substituted penicillin antibiotics BEECHAM GROUP P.L.C. (GB) 1990-04-17 — — US disclosed
EP-0254582-A2 6 Beta-(alpha-oximino)-acylamino penicillanic-acid derivatives and starting compounds BEECHAM GROUP PLC (GB) 1988-01-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents PNMT, NCL, NPM1 ALDH1A1 1805/4885TDP1 1841/4885KDM4E 1342/4885
US-20250188066-A1 ANTIVIRAL 1,3-DI-OXO-INDENE COMPOUNDS IRF3, EIF2AK2, ZC3HAV1 ALDH1A1 1239/4885TDP1 1037/4885KDM4E 3114/4885
US-12286423-B2 Antiviral 1,3-di-oxo-indene compounds IRF3, EIF2AK2, ZC3HAV1 ALDH1A1 1239/4885TDP1 1037/4885KDM4E 3114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.