Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1210867 | 0.79 | CYP2A6 (0.48) | CYP2A6TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL28403411 | 0.79 | CYP2A6 (0.56) | CYP2A6TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL1065739 | 0.77 | ALDH1A1 (0.41) | CYP2A6ALDH1A1HSD17B10HPGDBCL2L1 | |
| Methane SCHEMBL28759107 | 0.77 | CYP2A6 (0.46) | CYP2A6TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL8972805 | 0.76 | ABL1 (0.50) | TSHRALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL7380110 | 0.76 | ALDH1A1 (0.44) | CYP2A6ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL27926064 | 0.76 | CYP2A6 (0.44) | CYP2A6ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL7563629 | 0.76 | CYP2A6 (0.44) | CYP2A6TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL3278303 | 0.74 | KMT2A (0.47) | CYP2A6ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL8679281 | 0.74 | TYR (0.44) | CYP2A6ALDH1A1HSD17B10HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102399-B | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-116102399-A | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-116023209-A | Synthesis method of intermediate and process for preparing bifonazole | 重庆西南制药二厂有限责任公司 | 2023-04-28 | — | — | CN | claimed |
| CN-116102399-B | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-116102399-B | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-116102399-B | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-116102399-A | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-116102399-A | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-116102399-A | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-116023209-A | Synthesis method of intermediate and process for preparing bifonazole | 重庆西南制药二厂有限责任公司 | 2023-04-28 | — | — | CN | disclosed |
| US-RE41254-E1 | Synthesis procedure for biphenylimidazolyl-(1)-phenylmethane and related compounds | MANUFACTURAS HUMBERTO TO BUELE HIJOS, S. (SV) | 2010-04-20 | — | — | US | disclosed |
| US-7112681-B2 | Synthesis procedure for imidazolyl carbinol derivatives such as biphenylimidazolyl-(1)-phenylmethane | MANUFACTURAS HUMBERTO BUKELE E HIJOS, S.A DE C.V (SV) | 2006-09-26 | — | — | US | disclosed |
| US-6870057-B1 | Reducing 4-phenylbenzophenone to alcohols, then condensing the intermediates with imidazole, to form bifonazole used as fungicides | MANUFACTURAS HUMBERTO BUKELE E HIJOS, S.A. DE C.V. (SV) | 2005-03-22 | — | — | US | disclosed |
| US-20040267027-A1 | Synthesis procedure for biphenylimidazolyl-(1)-phenylmethane and related compounds | MANUFACTURAS HUMBERTO TO BUELE HIJOS, S. | 2004-12-30 | — | — | US | disclosed |
| WO-2001087848-A2 | SYNTHESIS PROCEDURE FOR BIPHENYLIMIDAZOLYL-(1)-PHENYLMETHANE AND RELATED COMPOUNDS | MANUFACTURAS HUMBERTO BUKELE E HIJOS, S.A. DE C.V. (US) | 2001-11-22 | — | — | WO | disclosed |
| US-4251540-A | Combating crop damaging fungi with α-(4-biphenylyl)-benzyl-azolium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-17 | — | — | US | disclosed |
| US-4243670-A | MICROBORICIDES; FUNGICIDES; SPORICIDES; HYGIENE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| US-4118487-A | ANTIMICROBIAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |