Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | BCR | P11274 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14622110 | 0.79 | ALDH1A1 (0.43) | MAPTRAB9ATSHRL3MBTL1MITF | |
| SCHEMBL28806943 | 0.79 | ALDH1A1 (0.51) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL13913541 | 0.79 | ABL1 (0.56) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL6807218 | 0.77 | ABL1 (0.55) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL3280004 | 0.76 | CYP2A6 (0.43) | HDAC4HDAC2HDAC8MAPTTSHR | |
| SCHEMBL874908 | 0.76 | ACP3 (0.56) | MAPTNPC1RAB9ATSHRL3MBTL1 | |
| SCHEMBL4457608 | 0.75 | KMT2A (0.48) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL12715050 | 0.75 | ABL1 (0.79) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL2277677 | 0.75 | CA1 (0.58) | MAPTNPC1RAB9ATSHRL3MBTL1 | |
| SCHEMBL27613425 | 0.75 | ABL1 (0.51) | ABL1ABCB1BCRHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416817-B1 | Amplification processes | ZENECA LTD (GB) | 1996-10-16 | — | — | EP | disclosed |
| US-5525494-A | Amplification processes | ZENECA LIMITED (GB) | 1996-06-11 | — | — | US | disclosed |
| EP-0416817-A2 | Amplification processes | ZENECA LIMITED (GB) | 1991-03-13 | — | — | EP | disclosed |