Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 5/20 | 0.36 |
| ▸ | VDR | P11473 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3280514 | 0.88 | VDR (0.41) | VDRCYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL4407806 | 0.87 | VDR (0.40) | VDRCYP4F2CYP4A11 | |
| SCHEMBL4399775 | 0.85 | VDR (0.38) | VDRCYP4F2CYP4A11 | |
| SCHEMBL4405455 | 0.85 | CYP4F2 (0.36) | CYP4F2CYP4A11MRGPRX4PPARGPPARA | |
| SCHEMBL4407512 | 0.84 | VDR (0.36) | VDR | |
| SCHEMBL4410313 | 0.84 | VDR (0.39) | VDR | |
| SCHEMBL6565030 | 0.83 | DAO (0.35) | — | |
| SCHEMBL6156234 | 0.82 | MAOB (0.39) | CYP4F2CYP4A11MRGPRX4MEN1KMT2A | |
| SCHEMBL6155834 | 0.80 | RARA (0.33) | CYP4F2CYP4A11MRGPRX4SLC7A5 | |
| SCHEMBL4399869 | 0.79 | VDR (0.40) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700657-B2 | Vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-04-20 | — | — | US | disclosed |
| EP-1395538-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2009-12-30 | — | — | EP | disclosed |
| US-20040224929-A1 | Novel vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-11-11 | — | — | US | disclosed |
| EP-1395538-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094754-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2002-11-28 | — | — | WO | disclosed |