SCHEMBL328060

SCHEMBL328060

C=CC(=O)NCCOC(=O)c1ccc(N(C)C)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.57
NPC1 O15118 4/20 0.57
ALDH1A1 P00352 10/20 0.50
HPGD P15428 5/20 0.50
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MAPK1 P28482 3/20 0.50
HSD17B10 Q99714 2/20 0.50
GAA P10253 1/20 0.50
TSHR P16473 1/20 0.50
MAPT P10636 6/20 0.48
L3MBTL1 Q9Y468 1/20 0.45
LMNA P02545 3/20 0.42
CYP3A4 P08684 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC8 Q9BY41 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2606300 0.81 RAB9A (0.63) RAB9ANPC1ALDH1A1HPGDKDM4E
SCHEMBL279033 0.80 ALDH1A1 (0.52) RAB9ANPC1ALDH1A1HPGDKDM4E
SCHEMBL23630890 0.80 RAB9A (0.61) RAB9ANPC1ALDH1A1HPGDKDM4E
SCHEMBL6414815 0.79 SERPINE1 (0.42) ALDH1A1HPGDMAPK1GAATSHR
SCHEMBL1506126 0.79 ALDH1A1 (0.65) RAB9ANPC1ALDH1A1HPGDKDM4E
SCHEMBL5305479 0.79 ALDH1A1 (0.54) RAB9ANPC1ALDH1A1HPGDKDM4E
SCHEMBL278833 0.78 HDAC1 (0.52) RAB9ANPC1ALDH1A1HPGDKDM4E
SCHEMBL5308929 0.77 ALDH1A1 (0.52) RAB9ANPC1ALDH1A1HPGDKDM4E
SCHEMBL14206324 0.77 RAB9A (0.58) RAB9ANPC1ALDH1A1HPGDKDM4E
SCHEMBL28899489 0.77 CA12 (0.51) KDM4EGAAMEN1KMT2AHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9796865-B2 Curable liquids and inks for toys and food packaging applications AGFA GRAPHICS NV (BE) 2017-10-24 US disclosed
EP-2189477-B1 Radiation curable compositions for food applications AGFA GRAPHICS NV (BE) 2017-07-19 EP disclosed
US-9416287-B2 Curable liquids and inks for toys and food packaging applications AGFA GRAPHICS NV (BE) 2016-08-16 US disclosed
US-9416287-B2 Curable liquids and inks for toys and food packaging applications AGFA GRAPHICS NV (BE) 2016-08-16 US disclosed
US-9249321-B2 Curable liquids and inks for toys and food packaging applications AGFA GRAPHICS NV (BE) 2016-02-02 US disclosed
US-20150050427-A1 CURABLE LIQUIDS AND INKS FOR TOYS AND FOOD PACKAGING APPLICATIONS AGFA NV (BE) 2015-02-19 US disclosed
US-8940811-B2 Curable liquids and inks for toys and food packaging applications AGFA GRAPHICS NV (BE) 2015-01-27 US disclosed
US-8940811-B2 Curable liquids and inks for toys and food packaging applications AGFA GRAPHICS NV (BE) 2015-01-27 US disclosed
US-20140050858-A1 CURABLE LIQUIDS AND INKS FOR TOYS AND FOOD PACKAGING APPLICATIONS AGFA GRAPHICS NV (BE) 2014-02-20 US disclosed
US-8563624-B2 Curable liquids and inks for toys and food packaging applications AGFA GRAPHICS NV (BE) 2013-10-22 US disclosed
US-8344038-B2 Radiation curable compositions for food applications AGFA GRAPHICS NV (BE) 2013-01-01 US disclosed
US-8344038-B2 Radiation curable compositions for food applications AGFA GRAPHICS NV (BE) 2013-01-01 US disclosed
US-20120108746-A1 RADIATION CURABLE INKJET PRINTING METHODS AGFA GRAPHICS NV (BE) 2012-05-03 US disclosed
US-8133551-B2 Radiation curable inkjet printing methods AGFA GRAPHICS NV (BE) 2012-03-13 US disclosed
US-20110124768-A1 CURABLE LIQUIDS AND INKS FOR TOYS AND FOOD PACKAGING APPLICATIONS AGFA GRAPHICS NV (BE) 2011-05-26 US disclosed
US-20100331478-A1 RADIATION CURABLE INKJET PRINTING METHODS AGFA GRAPHICS NV (BE) 2010-12-30 US disclosed
US-20100313782-A1 CURABLE LIQUIDS AND INKS FOR TOYS AND FOOD PACKAGING APPLICATIONS AGFA GRAPHICS NV (BE) 2010-12-16 US disclosed
US-20100313782-A1 CURABLE LIQUIDS AND INKS FOR TOYS AND FOOD PACKAGING APPLICATIONS AGFA GRAPHICS NV (BE) 2010-12-16 US disclosed
US-20100304149-A1 RADIATION CURABLE COMPOSITIONS FOR FOOD APPLICATIONS AGFA GRAPHICS NV (BE) 2010-12-02 US disclosed
US-20100304149-A1 RADIATION CURABLE COMPOSITIONS FOR FOOD APPLICATIONS AGFA GRAPHICS NV (BE) 2010-12-02 US disclosed