SCHEMBL3280831

SCHEMBL3280831

C=COP(=O)(O)CCOC(=O)C(=C)C

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2639352 0.81 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3281547 0.81 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL21091791 0.79 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL25967839 0.79 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1369304 0.79 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1532875 0.78 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL42001 0.78 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL975789 0.78 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3278847 0.77 TSHR (0.48) THRBTSHRALDH1A1
SCHEMBL19291628 0.77 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799741-B1 RADIATION CURABLE POWDER COATING COMPOSITIONS CYTEC SURFACE SPECIALTIES SA (BE) 2012-08-15 EP disclosed
CN-101035827-B Radiation curable powder coating compositions CYTEC SURFACE SPECIALTIES SA 2011-06-15 CN disclosed
US-7695773-B2 Radiation curable powder coating compositions CYTEC SURFACE SPECIALTIES, S.A. (BE) 2010-04-13 US disclosed
US-20080206480-A1 Radiation Curable Powder Coating Compositions ALLNEX BELGIUM S.A. (BE) 2008-08-28 US disclosed
CN-101035827-A Radiation curable powder coating compositions CYTEC SURFACE SPECIALTIES SA (BE) 2007-09-12 CN disclosed
EP-1799741-A1 RADIATION CURABLE POWDER COATING COMPOSITIONS CYTEC SURFACE SPECIALTIES, S.A. (BE) 2007-06-27 EP disclosed
WO-2006037493-A1 RADIATION CURABLE POWDER COATING COMPOSITIONS CYTEC SURFACE SPECIALTIES, S.A. (BE) 2006-04-13 WO disclosed
EP-1645583-A1 Radiation curable powder coating compositions CYTEC SURFACE SPECIALTIES, S.A. (BE) 2006-04-12 EP disclosed