SCHEMBL2639352

SCHEMBL2639352

C=C(C)C(=O)OCCP(=O)(O)OC(=O)C(=C)C

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
BTN3A1 O00481 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25967839 0.84 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1369304 0.84 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL21091791 0.84 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1532875 0.82 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL42001 0.82 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL975789 0.82 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL19291628 0.81 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
Ethylene SCHEMBL28716890 0.81 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3280831 0.81 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
Phosphoric Acid SCHEMBL836840 0.80 THRB (0.63) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4791042-B2 2011-10-12 JP claimed
EP-1401562-B1 PROCESS FOR THE FORMATION OF EMULSIONS SYNGENTA LTD (GB) 2008-10-08 EP claimed
US-7199185-B2 Use of reactive polymeric surfactants in the formation of emulsions SYNGENTA LIMITED (GB) 2007-04-03 US claimed
EP-1569512-B1 PARTICULATE SUSPENSIONS SYNGENTA LTD (GB) 2007-02-28 EP claimed
US-20060116290-A1 Particulate suspensions SYNGENTA CROP PROTECTION, INC. 2006-06-01 US claimed
EP-1569512-A2 PARTICULATE SUSPENSIONS Syngenta Limited (GB) 2005-09-07 EP claimed
CN-1541136-A Use of reactive polymeric surfactants in emulsion formation 2004-10-27 CN claimed
US-20040197357-A1 Use of reactive polymeric surfactants in the formation of emulsions SYNGENTA LIMITED (GB) 2004-10-07 US claimed
WO-2004052099-A2 PARTICULATE SUSPENSIONS SYNGENTA LIMITED (GB) 2004-06-24 WO claimed
EP-1401562-A2 USE OF REACTIVE POLYMERIC SURFACTANTS IN THE FORMATION OF EMULSIONS Syngenta Limited (GB) 2004-03-31 EP claimed
WO-2002100525-A2 USE OF REACTIVE POLYMERIC SURFACTANTS IN THE FORMATION OF EMULSIONS SYNGENTA LIMITED (GB) 2002-12-19 WO claimed
EP-1401562-B1 PROCESS FOR THE FORMATION OF EMULSIONS SYNGENTA LTD (GB) 2008-10-08 EP disclosed
US-7199185-B2 Use of reactive polymeric surfactants in the formation of emulsions SYNGENTA LIMITED (GB) 2007-04-03 US disclosed
EP-1569512-B1 PARTICULATE SUSPENSIONS SYNGENTA LTD (GB) 2007-02-28 EP disclosed
US-20060116290-A1 Particulate suspensions SYNGENTA CROP PROTECTION, INC. 2006-06-01 US disclosed
CN-1541136-A Use of reactive polymeric surfactants in emulsion formation 2004-10-27 CN disclosed
US-20040197357-A1 Use of reactive polymeric surfactants in the formation of emulsions SYNGENTA LIMITED (GB) 2004-10-07 US disclosed
WO-2004052099-A2 PARTICULATE SUSPENSIONS SYNGENTA LIMITED (GB) 2004-06-24 WO disclosed
EP-1401562-A2 USE OF REACTIVE POLYMERIC SURFACTANTS IN THE FORMATION OF EMULSIONS Syngenta Limited (GB) 2004-03-31 EP disclosed
WO-2002100525-A2 USE OF REACTIVE POLYMERIC SURFACTANTS IN THE FORMATION OF EMULSIONS SYNGENTA LIMITED (GB) 2002-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040197357-A1 Use of reactive polymeric surfactants in the formation of emulsions PHOSPHO1, APOB, LIPA THRB 2972/4885TSHR 4275/4885ALDH1A1 3971/4885
US-20060116290-A1 Particulate suspensions PFAS, VCL, JMJD7 THRB 4740/4885TSHR 4404/4885ALDH1A1 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.