Ethylene Glycol

Ethylene Glycol

SCHEMBL3280958

CCCCC/C=C\C/C=C\CCCCCCCC(=O)OCCOC(=O)CCCCCCC/C=C\C/C=C\CCCCC.OCCO

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.81
ALDH1A1 P00352 6/20 0.69
MAPT P10636 1/20 0.69
THRB P10828 1/20 0.69
CNR1 P21554 1/20 0.69
DGKA P23743 2/20 0.64
EPHX2 P34913 1/20 0.63
CYP3A4 P08684 2/20 0.61
ALOX15 P16050 2/20 0.61
TSHR P16473 2/20 0.61
HSD17B10 Q99714 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
FAAH O00519 2/20 0.60
F7 P08709 3/20 0.59
F3 P13726 3/20 0.59
KDM4E B2RXH2 2/20 0.59
PPARG P37231 2/20 0.59
PPARD Q03181 2/20 0.59
PPARA Q07869 2/20 0.59
DUSP3 P51452 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7639501 0.95 MGLL (0.77) MGLLALDH1A1MAPTTHRBCNR1
Ethylene Glycol SCHEMBL3286075 0.95 MGLL (0.72) MGLLALDH1A1MAPTTHRBCNR1
Ethylene Glycol SCHEMBL19064550 0.95 MGLL (0.72) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL3280959 0.94 MGLL (0.91) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL17685834 0.94 MGLL (0.91) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL28405410 0.94 MGLL (0.80) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL3660036 0.93 MGLL (0.78) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL17558128 0.93 MGLL (0.78) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL29513053 0.92 MGLL (0.94) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL10716785 0.92 MGLL (0.77) MGLLALDH1A1MAPTTHRBCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115844832-A Self-assembled nanoparticles of two small-molecule prodrugs capable of adjusting proportion and synchronously releasing two proto-drugs, preparation method and application 盐城工学院 2023-03-28 CN claimed
CN-104342090-A Lubricant for drilling fluid, and application thereof CHINA PETROLEUM & CHEMICAL 2015-02-11 CN claimed
CN-115624631-B Bufotalin prodrug self-assembled nanoparticle and preparation method and application thereof 盐城工学院 2024-10-01 CN disclosed
CN-109988349-B Rubber composition for tire outer layer and pneumatic tire 住友橡胶工业株式会社 2022-11-08 CN disclosed
CN-109549927-B Solid solution compositions and their use in cardiovascular disease 因佛斯特医疗有限公司 2022-03-29 CN disclosed
US-20210252024-A1 Cancer Drug and Uses HEALTH CLINICS LIMITED (GB) 2021-08-19 US disclosed
CN-104981253-B Solid solution composition and its purposes in chronic inflammation 因佛斯特医疗有限公司 2019-05-10 CN disclosed
CN-109549927-A Solid solution composition and its purposes in cardiovascular disease 因佛斯特医疗有限公司 2019-04-02 CN disclosed
CN-105007947-B solid solution compositions and their use in cardiovascular disease 因佛斯特医疗有限公司 2019-02-15 CN disclosed
US-10188668-B2 Cancer drug and uses HEALTH CLINICS LIMITED (GB) 2019-01-29 US disclosed
CN-104968368-B Solid solution compositions and their use in severe pain 因佛斯特医疗有限公司 2018-05-04 CN disclosed
CN-104981253-A Solid solution compositions and use in chronic inflammation BIOCOPEA LTD 2015-10-14 CN disclosed
CN-104968368-A Solid solution compositions and their use in severe pain INFIRST HEALTHCARE LTD 2015-10-07 CN disclosed
CN-104968330-A Compositions and methods for treating severe pain INFIRST HEALTHCARE LTD 2015-10-07 CN disclosed
CN-104342090-A Lubricant for drilling fluid, and application thereof CHINA PETROLEUM & CHEMICAL 2015-02-11 CN disclosed
US-7705084-B2 Water borne film-forming compositions THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2010-04-27 US disclosed
US-20070093579-A1 Water Borne Film-Forming Compositions THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2007-04-26 US disclosed
US-7160945-B1 Water borne film-forming compositions THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2007-01-09 US disclosed
US-20040039095-A1 Water borne film-forming compositions THE CURATORS OF THE UNIVERSITY OF MISSOURI 2004-02-26 US disclosed
EP-1169397-B1 WATER BORNE FILM-FORMING COMPOSITIONS UNIV MISSOURI (US) 2003-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10188668-B2 Cancer drug and uses NPC1L1, PCK2, NPC1 MGLL 120/4885ALDH1A1 1275/4885MAPT 716/4885
US-20210252024-A1 Cancer Drug and Uses NPC1L1, PCK2, NPC1 MGLL 120/4885ALDH1A1 1275/4885MAPT 716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.