Naphthalene

Naphthalene

SCHEMBL3281278

C=O.O=[PH](O)O.c1ccc2ccccc2c1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.50
ALOX12 P18054 2/20 0.50
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CYP1A2 P05177 4/20 0.38
ALDH1A1 P00352 4/20 0.37
HSD17B10 Q99714 4/20 0.37
TDP1 Q9NUW8 3/20 0.37
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 2/20 0.37
HPGD P15428 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP3A4 P08684 2/20 0.37
EGFR P00533 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
ALOX15 P16050 1/20 0.37
JAK1 P23458 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL3285009 0.94 CYP2A6 (0.57) CYP2A6ALOX12CES2CES1CYP1A2
Naphthalene SCHEMBL31456246 0.94 CYP2A6 (0.57) CYP2A6ALOX12CES2CES1CYP1A2
Anthracene SCHEMBL3281536 0.88 CES2 (0.41) CYP2A6ALOX12CES2CES1CYP1A2
Naphthalene SCHEMBL8366099 0.83 CYP2A6 (0.73) CYP2A6ALOX12CES2CES1CYP1A2
Naphthalene SCHEMBL194159 0.83 CYP2A6 (0.73) CYP2A6ALOX12CES2CES1CYP1A2
Anthracene SCHEMBL3281461 0.81 CES2 (0.44) CYP2A6ALOX12CES2CES1CYP1A2
Naphthalene SCHEMBL28051541 0.80 CYP2A6 (0.57) CYP2A6ALOX12CES2CES1CYP1A2
Naphthalene SCHEMBL4409490 0.79 CYP2A6 (0.67) CYP2A6ALOX12CES2CES1CYP1A2
Naphthalene SCHEMBL28221901 0.79 CYP2A6 (0.47) CYP2A6ALOX12CES2CES1CYP1A2
Benz(B)Anthracene SCHEMBL27925179 0.79 ALDH1A1 (0.46) CYP2A6ALOX12CES2CES1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7704939-B2 Surfactant SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2010-04-27 US disclosed
US-20070167343-A1 neutralized salt including alkylbenzenesulphonates (toluenesulfonic acid guanidine salt, toluenesulfonic acid DBU salt, toluenesulfonic acid DBN salt) for cleaning electonics SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2007-07-19 US disclosed