SCHEMBL3281870

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3281204	0.80	CCR3 (0.43)	NAMPTCCR3ROCK2ROCK1KMT2A
	SCHEMBL3281862	0.77	CCR3 (0.48)	NAMPTCCR3KDM4EROCK2ROCK1
	SCHEMBL3286069	0.75	CCR3 (0.46)	NAMPTCCR3ROCK2ROCK1KMT2A
	SCHEMBL3281236	0.74	CCR3 (0.62)	CCR3KMT2AEPHX2MEN1
	SCHEMBL3282029	0.74	CCR3 (0.58)	CCR3KMT2AEPHX2MEN1
	SCHEMBL3283195	0.74	CCR3 (0.46)	CCR3EPHX2LMNAMAPT
	SCHEMBL3287726	0.73	LMNA (0.48)	NAMPTCCR3ROCK2ROCK1KMT2A
	SCHEMBL3282930	0.73	CCR3 (0.72)	CCR3EPHX2
	SCHEMBL3282360	0.72	CCR3 (0.62)	CCR3KDM4EKMT2AEPHX2
	SCHEMBL3282373	0.71	CCR3 (0.61)	CCR3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.