SCHEMBL328198

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10035939	0.94	MAPT (0.56)	ALDH1A1MAPTGAAMEN1THRB
	SCHEMBL188287	0.91	MAPT (0.63)	ALDH1A1MAPTGAAMEN1THRB
	SCHEMBL1812259	0.88	ALDH1A1 (0.64)	ALDH1A1MAPTGAAMEN1THRB
	SCHEMBL15244439	0.86	MAPT (0.70)	ALDH1A1MAPTGAAMEN1THRB
	SCHEMBL24124031	0.85	GAA (0.50)	ALDH1A1MAPTGAAHTTLMNA
	SCHEMBL10126824	0.85	ALDH1A1 (0.69)	ALDH1A1MAPTGAAMEN1THRB
	SCHEMBL29477783	0.85	ALDH1A1 (0.71)	ALDH1A1MAPTGAAMEN1THRB
	SCHEMBL187881	0.85	ALDH1A1 (0.71)	ALDH1A1MAPTGAAMEN1THRB
	SCHEMBL10128072	0.84	ALDH1A1 (0.54)	ALDH1A1MAPTGAAMEN1THRB
	SCHEMBL24301307	0.84	MAPT (0.52)	ALDH1A1MAPTGAAMEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.