Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417368 | 0.83 | PSMB8 (0.58) | PSMB8PSMB5L3MBTL1CA2CA12 | |
| SCHEMBL3282188 | 0.81 | PSMB8 (0.55) | PSMB8PSMB5L3MBTL1CA2CA12 | |
| SCHEMBL4357765 | 0.80 | PSMB8 (0.51) | PSMB8PSMB5L3MBTL1CA2CA12 | |
| SCHEMBL10700457 | 0.79 | ALDH1A1 (0.63) | PSMB8PSMB5L3MBTL1CA2CA12 | |
| SCHEMBL31546243 | 0.78 | PSMB8 (0.53) | PSMB8PSMB5L3MBTL1CA2CA12 | |
| SCHEMBL8799542 | 0.78 | CA1 (0.55) | PSMB8PSMB5L3MBTL1CA2CA12 | |
| SCHEMBL4883388 | 0.78 | PSMB8 (0.53) | PSMB8PSMB5L3MBTL1CA2CA12 | |
| SCHEMBL8229512 | 0.78 | PSMB8 (0.64) | PSMB8PSMB5L3MBTL1CA2CA12 | |
| SCHEMBL10474769 | 0.78 | PSMB8 (0.64) | PSMB8PSMB5L3MBTL1CA2CA12 | |
| SCHEMBL21873110 | 0.77 | PSMB8 (0.51) | PSMB8PSMB5L3MBTL1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |