Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413794 | 0.81 | TSHR (0.48) | TSHRRGS12BACE1TDP1LMNA | |
| SCHEMBL3877151 | 0.81 | TSHR (0.48) | TSHRRGS12BACE1TDP1LMNA | |
| SCHEMBL8415882 | 0.81 | TSHR (0.48) | TSHRRGS12BACE1TDP1LMNA | |
| SCHEMBL10914312 | 0.77 | TSHR (0.44) | TSHRRGS12BACE1TDP1LMNA | |
| SCHEMBL20435093 | 0.77 | TSHR (0.44) | TSHRRGS12BACE1TDP1LMNA | |
| SCHEMBL941641 | 0.74 | TSHR (0.41) | TSHRLMNA | |
| SCHEMBL7760124 | 0.72 | TSHR (0.40) | TSHRRGS12LMNA | |
| SCHEMBL6951527 | 0.71 | TSHR (0.38) | TSHR | |
| SCHEMBL6951524 | 0.70 | — | — | |
| SCHEMBL112153 | 0.68 | TSHR (0.40) | TSHRRGS12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4124171-A | — | — | None | — | — | JP | disclosed |
| CN-101274907-B | Process for producing methionine | SUMITOMO CHEMICAL CO | 2013-02-06 | — | — | CN | disclosed |
| US-7709235-B2 | 5-Substituted hydantoin racemase, DNA encoding the same, recombinant DNA, transformed cell, and process for production of optically active N-carbamylamino acid or optically active amino acid | KANEKA CORPORATION (JP) | 2010-05-04 | — | — | US | disclosed |
| US-20080261268-A1 | 5-Substituted Hydantoin Racemase, Dna Encoding the Same, Recombinant Dna, Transformed Cell, and Process for Production of Optically Active N-Carbamylamino Acid or Optically Active Amino Acid | KANEKA CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |
| CN-101274907-A | Process for producing methionine | SUMITOMO CHEMICAL CO (JP) | 2008-10-01 | — | — | CN | disclosed |
| EP-1852510-A1 | 5-SUBSTITUTED HYDANTOIN RACEMASE, DNA ENCODING THE SAME, RECOMBINANT DNA, TRANSFORMED CELL, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE N-CARBAMYLAMINO ACID OR OPTICALLY ACTIVE AMINO ACID | Kaneka Corporation (JP) | 2007-11-07 | — | — | EP | disclosed |
| EP-0400638-B1 | Process for the preparation of D-alpha aminocarboxylic acids | DEGUSSA (DE) | 1994-10-05 | — | — | EP | disclosed |
| JP-H04124171-A | PRODUCTION OF METHIONINE | SUMITOMO CHEM CO LTD | 1992-04-24 | — | — | JP | disclosed |
| US-4980284-A | Method of preparing D-α-amino acids | DEGUSSA AG (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0400638-A1 | Process for the preparation of D-alpha aminocarboxylic acids | DEGUSSA AG (DE) | 1990-12-05 | — | — | EP | disclosed |