Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941641 | 0.82 | TSHR (0.41) | TSHRHSD17B10LMNA | |
| SCHEMBL10914312 | 0.77 | TSHR (0.44) | TSHRHSD17B10RGS12LMNA | |
| SCHEMBL3877151 | 0.76 | TSHR (0.48) | TSHRRGS12LMNA | |
| SCHEMBL8413794 | 0.76 | TSHR (0.48) | TSHRRGS12LMNA | |
| SCHEMBL8415882 | 0.76 | TSHR (0.48) | TSHRRGS12LMNA | |
| SCHEMBL10419736 | 0.74 | TSHR (0.32) | TSHR | |
| SCHEMBL3282408 | 0.72 | TSHR (0.44) | TSHRRGS12LMNA | |
| SCHEMBL20435093 | 0.72 | TSHR (0.44) | TSHRRGS12LMNA | |
| SCHEMBL112153 | 0.72 | TSHR (0.40) | TSHRHSD17B10RGS12GAALMNA | |
| SCHEMBL3133745 | 0.70 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780125-B1 | Use of hydantoin derivatives for the preparation of a medicament for the treatment of dieases associated with the presence of active oxygen and free radicals | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2001-04-18 | — | — | EP | disclosed |
| EP-0160618-A1 | Hydantoin derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |