Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3288997 | 0.87 | NAAA (0.52) | NAAADGKAALDH1A1HCAR2TP53 | |
| SCHEMBL3281819 | 0.86 | NAAA (0.55) | NAAADGKAALDH1A1HCAR2LMNA | |
| SCHEMBL25145344 | 0.85 | HCAR2 (0.37) | NAAADGKAALDH1A1PPM1BPTPN1 | |
| SCHEMBL2187425 | 0.81 | ALDH1A1 (0.35) | NAAADGKAALDH1A1PPM1BPTPN1 | |
| SCHEMBL2910833 | 0.81 | NAAA (0.40) | NAAADGKAALDH1A1PPM1BPTPN1 | |
| SCHEMBL2911788 | 0.80 | ALDH1A1 (0.38) | NAAADGKAALDH1A1PPM1BPTPN1 | |
| SCHEMBL6343837 | 0.80 | ALDH1A1 (0.37) | NAAADGKAALDH1A1PPM1BPTPN1 | |
| SCHEMBL3282924 | 0.80 | GAA (0.44) | ALDH1A1LMNA | |
| SCHEMBL29033466 | 0.79 | CYP1A2 (0.42) | ALDH1A1 | |
| SCHEMBL28499700 | 0.78 | NAAA (0.37) | NAAADGKAALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100172851-A1 | Hydroxy-oligocarboxylic esters: effects on nerve and use for cutaneous and mucocutaneous organs or sites | YU RUEY J | 2010-07-08 | — | — | US | disclosed |
| US-7709014-B2 | Hydroxy-oligocarboxylic esters: effects on nerve and use for cutaneous and mucocutaneous organs or sites | YU RUEY J | 2010-05-04 | — | — | US | disclosed |
| EP-1937246-A2 | HYDROXY-OLIGOCARBOXYLIC ESTERS: EFFECTS ON NERVE AND USE FOR CUTANEOUS AND MUCOCUTANEOUS ORGANS OR SITES | Yu, Ruey J., Dr. (US) | 2008-07-02 | — | — | EP | disclosed |
| US-20070093551-A1 | Hydroxy-oligocarboxylic esters: effects on nerve and use for cutaneous and mucocutaneous organs or sites | YU RUEY J | 2007-04-26 | — | — | US | disclosed |
| WO-2007047486-A2 | HYDROXY-OLIGOCARBOXYLIC ESTERS: EFFECTS ON NERVE AND USE FOR CUTANEOUS AND MUCOCUTANEOUS ORGANS OR SITES | YU RUEY J (US) | 2007-04-26 | — | — | WO | disclosed |