SCHEMBL3282858

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15196505	0.85	NPC1 (0.39)	CCR3NPC1SMN1; SMN2RAB9ACYP1A2
	SCHEMBL3282930	0.81	CCR3 (0.72)	CCR3SMN1; SMN2EPHX2ALDH1A1HTT
	SCHEMBL8761037	0.79	CTSC (0.55)	NPC1SMN1; SMN2RAB9ACYP1A2CYP2C9
	SCHEMBL8760971	0.79	ALDH1A1 (0.65)	NPC1SMN1; SMN2RAB9ACYP1A2CYP2C9
	SCHEMBL3281892	0.77	CCR3 (0.52)	CCR3NPC1SMN1; SMN2RAB9AEPHX2
	SCHEMBL3282360	0.77	CCR3 (0.62)	CCR3SMN1; SMN2EPHX2KMT2AALDH1A1
	SCHEMBL3281062	0.77	CCR3 (0.62)	CCR3SMN1; SMN2EPHX2ALDH1A1HTT
	SCHEMBL3282262	0.76	CCR3 (0.61)	CCR3SMN1; SMN2CYP1A2CYP2C9EPHX2
	SCHEMBL3282373	0.76	CCR3 (0.61)	CCR3NPC1SMN1; SMN2RAB9AEPHX2
	SCHEMBL3281068	0.76	CCR3 (0.51)	CCR3NPC1SMN1; SMN2RAB9AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.