Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 9/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3276825 | 0.99 | DRD2 (0.45) | DRD2PDCD1CD274S1PR1SSTR4 | |
| SCHEMBL3281172 | 0.81 | PRCP (0.51) | DRD2S1PR1SSTR4PRCPMAOB | |
| Hydrochloric Acid SCHEMBL3283120 | 0.80 | PRCP (0.50) | DRD2S1PR1SSTR4PRCPMAOB | |
| Hydrochloric Acid SCHEMBL3277138 | 0.79 | S1PR1 (0.42) | S1PR1SSTR4PRCPSSTR1SSTR2 | |
| SCHEMBL3280090 | 0.76 | DRD2 (0.45) | DRD2CD274S1PR1SSTR4GSK3A | |
| Hydrochloric Acid SCHEMBL3276504 | 0.76 | SSTR4 (0.43) | S1PR1SSTR4SSTR1SSTR2SSTR3 | |
| Hydrochloric Acid SCHEMBL3277402 | 0.75 | DRD2 (0.44) | DRD2S1PR1SSTR4GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL3277561 | 0.75 | LTK (0.40) | S1PR1SSTR4GSK3AGSK3BSSTR1 | |
| Hydrochloric Acid SCHEMBL3282599 | 0.74 | SSTR4 (0.42) | CD274S1PR1SSTR4PRCP | |
| Hydrochloric Acid SCHEMBL3280920 | 0.73 | SSTR4 (0.39) | S1PR1SSTR4GSK3AGSK3BSSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123644-B1 | BENZOXAZEPINE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2014-12-17 | — | — | EP | disclosed |
| US-8247403-B2 | Benzoxazepine derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20100087418-A1 | BENZOXAZEPINE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2010-04-08 | — | — | US | disclosed |
| EP-2123644-A1 | BENZOXAZEPINE DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087418-A1 | BENZOXAZEPINE DERIVATIVES AND USE THEREOF | HTR2C, HTR5A, HTR2B | DRD2 296/4885PDCD1 3579/4885CD274 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.