Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PPM1B | O75688 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LGMN | Q99538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826452 | 1.00 | MAPT (0.51) | MAPTSMYD3ALDH1A1PPM1BPTPN1 | |
| SCHEMBL852813 | 1.00 | MAPT (0.51) | MAPTSMYD3ALDH1A1PPM1BPTPN1 | |
| Hydrochloric Acid SCHEMBL385320 | 0.98 | MAPT (0.50) | MAPTSMYD3ALDH1A1PPM1BPTPN1 | |
| Hydrochloric Acid SCHEMBL4714966 | 0.98 | MAPT (0.50) | MAPTSMYD3ALDH1A1PPM1BPTPN1 | |
| Hydrochloric Acid SCHEMBL4714961 | 0.98 | MAPT (0.50) | MAPTSMYD3ALDH1A1PPM1BPTPN1 | |
| Hydrochloric Acid SCHEMBL853961 | 0.98 | MAPT (0.50) | MAPTSMYD3ALDH1A1PPM1BPTPN1 | |
| Hydrochloric Acid SCHEMBL3195558 | 0.98 | MAPT (0.50) | MAPTSMYD3ALDH1A1PPM1BPTPN1 | |
| SCHEMBL8891623 | 0.89 | MAPT (0.60) | MAPTALDH1A1PPM1BPTPN1PPP1CC | |
| SCHEMBL2375356 | 0.89 | MAPT (0.60) | MAPTALDH1A1PPM1BPTPN1PPP1CC | |
| SCHEMBL4221 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283009-B1 | INHIBITORS OF JNK | HOFFMANN LA ROCHE (CH) | 2012-08-29 | — | — | EP | claimed |
| US-8183254-B2 | Inhibitors of JNK | ROCHE PALO ALTO LLC (US) | 2012-05-22 | — | — | US | claimed |
| EP-2283009-A1 | INHIBITORS OF JNK | F. Hoffmann-La Roche AG (CH) | 2011-02-16 | — | — | EP | claimed |
| US-20090318484-A1 | Inhibitors of JNK | ROCHE PALO ALTO LLC | 2009-12-24 | — | — | US | claimed |
| WO-2009138340-A1 | INHIBITORS OF JNK | F. HOFFMANN-LA ROCHE AG (CH) | 2009-11-19 | — | — | WO | claimed |
| US-20260078127-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | BOEHRINGER INGELHEIM INT (DE) | 2026-03-19 | — | — | US | disclosed |
| US-12459931-B2 | Benzothiophene derivative regulator, preparation method therefor and use thereof | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2025-11-04 | — | — | US | disclosed |
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-114645027-B | Aminotransferase mutant from bacillus megatherium and application thereof | 上海合全药物研发有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-113166135-B | Benzothiophene derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-114423753-B | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-116120213-B | Synthesis method of trans-4- (tert-butoxycarbonylamino) cyclohexane carboxylic acid | 重庆医药高等专科学校 | 2024-09-13 | — | — | CN | disclosed |
| US-5036104-A | ENZYME INHIBITORS | PFIZER INC. (US) | 1991-07-30 | — | — | US | disclosed |
| US-5030654-A | Glutaramide diuretic agents | PFIZER INC. (US) | 1991-07-09 | — | — | US | disclosed |
| US-4960792-A | HYPOTENSIVE AGENTS | PFIZER INC. (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0343911-A2 | Cycloalkyl-substituted glutaramide diuretic agents | Pfizer Limited (GB) | 1989-11-29 | — | — | EP | disclosed |
| EP-0342850-A1 | Enantiomeric glutaramide diuretic agents | Pfizer Limited (GB) | 1989-11-23 | — | — | EP | disclosed |
| EP-0274234-A2 | Spiro-subsituted glutaramide diuretic agents | Pfizer Limited (GB) | 1988-07-13 | — | — | EP | disclosed |
| US-4148798-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1979-04-10 | — | — | US | disclosed |
| US-3975403-A | Sulfur-containing ring compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318484-A1 | Inhibitors of JNK | MAPK1, MAP3K6, MAP3K1 | MAPT 1968/4885SMYD3 1902/4885ALDH1A1 4538/4885 |
| US-20260078127-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | CD38, CD22, CD79B | MAPT 4832/4885SMYD3 3059/4885ALDH1A1 877/4885 |
| US-12459931-B2 | Benzothiophene derivative regulator, preparation method therefor and use thereof | GPER1, GABRQ, GPR39 | MAPT 876/4885SMYD3 4553/4885ALDH1A1 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.