Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12909320 | 0.95 | BCL2L1 (0.46) | MAOAMAOBBCL2L1BADAR | |
| SCHEMBL10802712 | 0.87 | BCL2L1 (0.50) | MAOAMAOBBCL2L1BADAR | |
| SCHEMBL31598395 | 0.84 | DRD4 (0.42) | MAOAMAOBTP53KDM4EHPGD | |
| SCHEMBL5029748 | 0.84 | DRD4 (0.42) | MAOAMAOBTP53KDM4EHPGD | |
| SCHEMBL3283307 | 0.81 | BCL2L1 (0.56) | MAOAMAOBBCL2L1BADAR | |
| SCHEMBL29851805 | 0.78 | RXRA (0.39) | MAOAMAOBBCL2L1BADTP53 | |
| SCHEMBL19322587 | 0.78 | RXRA (0.39) | MAOAMAOBBCL2L1BADTP53 | |
| SCHEMBL22271609 | 0.76 | MAOA (0.43) | MAOAMAOBTP53TDP1KDM4E | |
| SCHEMBL16518067 | 0.74 | PNMT (0.40) | MAOAMAOBKDM4EADRA2A | |
| SCHEMBL14481407 | 0.74 | CYP1A2 (0.38) | MAOAMAOBTP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239761-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20240239761-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2024-07-18 | — | — | US | disclosed |
| EP-4310077-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | Medshine Discovery Inc. (CN) | 2024-01-24 | — | — | EP | disclosed |
| US-11041027-B2 | Polymerization process for producing ethylene based polymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-06-22 | — | — | US | disclosed |
| US-11041027-B2 | Polymerization process for producing ethylene based polymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-06-22 | — | — | US | disclosed |
| CN-107787336-B | Polymerization process for preparing ethylene-based polymers | 陶氏环球技术有限责任公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-107922538-B | Polymerization process for the preparation of ethylene-based polymers | 陶氏环球技术有限责任公司 | 2021-05-25 | — | — | CN | disclosed |
| EP-3736299-A1 | A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS | Dow Global Technologies Llc (US) | 2020-11-11 | — | — | EP | disclosed |
| EP-3736299-A1 | A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS | Dow Global Technologies Llc (US) | 2020-11-11 | — | — | EP | disclosed |
| EP-3317312-B1 | A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-06-10 | — | — | EP | disclosed |
| US-20050124692-A1 | Dihydrobenzofuranyl alkanamines and methods for using same as cns agents | WYETH (US) | 2005-06-09 | — | — | US | disclosed |
| WO-2005040146-A1 | DIHYDROBENZOFURANYL ALKANAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WYETH (US) | 2005-05-06 | — | — | WO | disclosed |
| CN-1115334-C | Pyridine derivative and medicine containing the same | OTSUKA PHARMA CO LTD (JP) | 2003-07-23 | — | — | CN | disclosed |
| US-6511995-B1 | Inhibits collagen synthesis, which is useful for prophylaxis or treatment of fibrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |
| CN-1294581-A | Pyridine derivative and pharmaceutical contg. same | OTSUKA PHARMA CO LTD (JP) | 2001-05-09 | — | — | CN | disclosed |
| EP-1066261-A1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999048871-A1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-30 | — | — | WO | disclosed |
| EP-0003664-B1 | ALKANOLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-17 | — | — | EP | disclosed |
| US-4275058-A | 1-(7-METHYLINDAN-4-YLOXY)-3-ISOPROPYLAMINOBUTAN-2-OL | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-06-23 | — | — | US | disclosed |
| EP-0003664-A1 | Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124692-A1 | Dihydrobenzofuranyl alkanamines and methods for using same as cns agents | HTR2C, HTR1A, HTR1B | MAOA 68/4885MAOB 47/4885BCL2L1 2673/4885 |
| US-20240239761-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | CYP3A43, CYP11B2, UGT2B7 | MAOA 320/4885MAOB 135/4885BCL2L1 3207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.