Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320055 | 0.83 | THRB (0.55) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL5175653 | 0.82 | THRB (0.42) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL9634091 | 0.82 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL21314238 | 0.81 | THRB (0.46) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL2320779 | 0.79 | THRB (0.48) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL27880069 | 0.79 | TSHR (0.50) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL29380620 | 0.78 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL2784396 | 0.78 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10892651 | 0.78 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL29597270 | 0.77 | THRB (0.49) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531889-B1 | USE OF A PHOTOPOLYMER FORMULATION WITH ESTER-BASED WRITING MONOMERS FOR THE FABRICATION OF HOLOGRAPHIC MEDIA | COVESTRO DEUTSCHLAND AG (DE) | 2020-06-03 | — | — | EP | disclosed |
| EP-0694298-B1 | PREFORMED GLASS IONOMER FILLER WHICH CAN SUSTAINEDLY RELEASE FLUORIDE ION AND DENTAL COMPOSITION CONTAINING THE SAME | SHOFU INC (JP) | 2010-06-09 | — | — | EP | disclosed |
| US-5883153-A | SUSTAINED RELEASE GLASS IONOMERS | SHOFU INC. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0694298-A1 | PREFORMED GLASS IONOMER FILLER WHICH CAN SUSTAINEDLY RELEASE FLUORIDE ION AND DENTAL COMPOSITION CONTAINING THE SAME | SHOFU INC. (JP) | 1996-01-31 | — | — | EP | disclosed |