SCHEMBL5175653

SCHEMBL5175653

C=CC(=O)OCCc1cc(C(=O)O)cc(C(=O)O)c1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.42
TSHR P16473 6/20 0.41
ALDH1A1 P00352 4/20 0.41
TP53 P04637 2/20 0.41
HIF1A Q16665 2/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.35
GAA P10253 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1265099 0.91 TSHR (0.45) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL2320779 0.83 THRB (0.48) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL3283448 0.82 THRB (0.46) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL21314238 0.80 THRB (0.46) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL1269730 0.80 POLB (0.45) THRBTSHRALDH1A1
SCHEMBL57853 0.79 THRB (0.50) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL29612237 0.79 THRB (0.50) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL106660 0.78 ALDH1A1 (0.40) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL1263541 0.78 THRB (0.47) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL5571975 0.77 PLA2G2A (0.33) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-12-26 US claimed
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-07-04 US claimed
EP-4331557-A1 RADICALLY POLYMERIZABLE COMPOSITION COMPRISING A REDOX INITIATOR SYSTEM BASED ON DIHYDROPYRIDINES Ivoclar Vivadent AG (LI) 2024-03-06 EP claimed
EP-4331558-A1 BIOCOMPATIBLE MELT-DENTIN SINGLE COMPONENT ADHESIVES Ivoclar Vivadent AG (LI) 2024-03-06 EP claimed
US-20240065944-A1 Biocompatible Enamel-Dentin Single-Component Adhesives IVOCLAR VIVADENT AG (LI) 2024-02-29 US claimed
EP-4312947-A1 SELF-ADHESIVE FISSURE SEALANT Kulzer GmbH (DE) 2024-02-07 EP claimed
US-20220362201-A1 AGENT FOR PROMOTING ODONTOBLAST PROPAGATION AND DIFFERENTIATION SUN MEDICAL CO., LTD. (JP) 2022-11-17 US claimed
WO-2022207879-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2022-10-06 WO claimed
EP-4049678-A1 AGENT FOR PROMOTING ODONTOBLAST PROPAGATION AND DIFFERENTIATION Sun Medical Co., Ltd. (JP) 2022-08-31 EP claimed
CN-114514010-A Odontoblast proliferation/differentiation promoter 尚美德齿科材料有限公司 2022-05-17 CN claimed
WO-2021079988-A1 AGENT FOR PROMOTING ODONTOBLAST PROPAGATION AND DIFFERENTIATION サンメディカル株式会社 2021-04-29 WO claimed
EP-4745210-A1 FLUORORUBBER TACKINESS AGENT COMPOSITION Unimatec Co., Ltd. (JP) 2026-05-20 EP disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4029839-B1 GLASS POWDER AND CHEMICAL POLYMERIZATION INITIATOR G C DENTAL IND CORP (JP) 2026-05-06 EP disclosed
US-20260083644-A1 METHOD FOR PRODUCING DENTAL POLYMERIZABLE COMPOSITION OR DENTAL POLYMERIZABLE COMPOSITION INTERMEDIATE SHOFU INC (JP) 2026-03-26 US disclosed
WO-2016026915-A1 LIGHT-CURING DENTAL COMPOSITE WITH INCREASING OPACITY IVOCLAR VIVADENT AG (LI) 2016-02-25 WO disclosed
WO-2015139811-A1 MONOMER MIXTURES FOR PRODUCING DENTAL MATERIALS IVOCLAR VIVADENT AG (LI) 2015-09-24 WO disclosed
WO-2015140276-A1 PHOTOPOLYMERISABLE AND DUAL CURING DENTAL MATERIALS BASED ON THIOUREA DERIVATIVES IVOCLAR VIVADENT AG (LI) 2015-09-24 WO disclosed
EP-1462079-B1 Dental composition G C DENTAL IND CORP (JP) 2007-05-23 EP disclosed
US-5854318-A Cement additive, method for producing the same, and cement composition NIPPON SHOKUBAI KAGAKU KOGYO CO, LTD. (JP) 1998-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083644-A1 METHOD FOR PRODUCING DENTAL POLYMERIZABLE COMPOSITION OR DENTAL POLYMERIZABLE COMPOSITION INTERMEDIATE ARCN1, LBR, POLL THRB 1247/4885TSHR 3634/4885ALDH1A1 2312/4885
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS THRB 894/4885TSHR 1186/4885ALDH1A1 318/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL THRB 2959/4885TSHR 4185/4885ALDH1A1 668/4885
US-20220362201-A1 AGENT FOR PROMOTING ODONTOBLAST PROPAGATION AND DIFFERENTIATION MKI67, MYADM, HGF THRB 1537/4885TSHR 4148/4885ALDH1A1 2490/4885
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS THRB 894/4885TSHR 1186/4885ALDH1A1 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.