Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | DRD5 | P21918 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3910326 | 0.87 | AR (0.67) | ARNR3C1METAP1ALDH1A1LMNA | |
| SCHEMBL3910141 | 0.84 | AR (0.72) | ARNR3C1METAP1ALDH1A1LMNA | |
| SCHEMBL6565555 | 0.82 | AR (0.69) | ARNR3C1METAP1ALDH1A1LMNA | |
| SCHEMBL6249986 | 0.80 | AR (0.67) | ARNR3C1ALDH1A1LMNACYP3A4 | |
| SCHEMBL3284563 | 0.79 | AR (1.00) | ARNR3C1BACE1MAOB | |
| SCHEMBL3288674 | 0.79 | AR (1.00) | ARNR3C1BACE1MAOB | |
| SCHEMBL3285403 | 0.77 | AR (0.50) | ARNR3C1ALDH1A1LMNACYP2C19 | |
| SCHEMBL12272588 | 0.77 | AR (0.63) | ARNR3C1ALDH1A1LMNAKDM1A | |
| SCHEMBL12272913 | 0.77 | AR (0.63) | ARNR3C1ALDH1A1LMNAKDM1A | |
| SCHEMBL12273326 | 0.77 | AR (0.63) | ARNR3C1ALDH1A1LMNAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713989-B2 | Glucocorticoid receptor modulators | DOW ROBERT L | 2010-05-11 | — | — | US | disclosed |
| US-20070117805-A1 | Glucocorticoid receptor modulators | PFIZER INC. | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117805-A1 | Glucocorticoid receptor modulators | NR3C1, NR3C2, MC2R | AR 84/4885NR3C1 1/4885METAP1 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.