⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10888847 | 0.74 | — | — | |
| SCHEMBL13558469 | 0.74 | — | — | |
| SCHEMBL8771883 | 0.71 | — | — | |
| SCHEMBL150679 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL672469 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL114625 | 0.65 | — | — | |
| SCHEMBL28821507 | 0.65 | ALDH1A1 (0.41) | — | |
| SCHEMBL28329124 | 0.65 | ALDH1A1 (0.41) | — | |
| SCHEMBL322207 | 0.65 | — | — | |
| SCHEMBL182079 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776632-B | A helicobacter pylori O: synthesis method of 6 serotype O-antigen sugar chain | 江南大学 | 2021-01-29 | — | — | CN | disclosed |
| EP-2258708-A1 | Macrolide compounds endowed with antiinflammatory activity | Zambon S.p.A. (IT) | 2010-12-08 | — | — | EP | disclosed |
| US-7704960-B2 | Macrolide compounds endowed with antiinflammatory activity | ZAMBON GROUP S.P.A. (IT) | 2010-04-27 | — | — | US | disclosed |
| US-20090054357-A1 | MACROLIDE COMPOUNDS ENDOWED WITH ANTIINFLAMMATORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2009-02-26 | — | — | US | disclosed |
| US-7488811-B2 | Macrolide compounds endowed with antiinflammatory activity | ZAMBON GROUP S.P.A. (IT) | 2009-02-10 | — | — | US | disclosed |
| US-20060058246-A1 | Macrolide compounds endowed with antiinflammatory activity | ZAMBON GROUP S.P.A. (IT) | 2006-03-16 | — | — | US | disclosed |
| EP-1529053-A2 | MACROLIDE COMPOUNDS ENDOWED WITH ANTIINFLAMMATORY ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004013153-A2 | MACROLIDE COMPOUNDS ENDOWED WITH ANTIINFLAMMATORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2004-02-12 | — | — | WO | disclosed |