SCHEMBL328475

SCHEMBL328475

CC(=O)NC(Cc1ccc(O)c(O)c1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.60
ACE P12821 1/20 0.60
KDM4E B2RXH2 4/20 0.59
ALOX15 P16050 4/20 0.59
HIF1A Q16665 4/20 0.59
HSD17B10 Q99714 4/20 0.59
RECQL P46063 3/20 0.59
LCK P06239 2/20 0.59
USP2 O75604 2/20 0.59
ADORA3 P0DMS8 2/20 0.59
PTGS1 P23219 2/20 0.59
HTR2A P28223 2/20 0.59
PTGS2 P35354 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
EGFR P00533 1/20 0.59
FYN P06241 1/20 0.59
SLC7A5 Q01650 1/20 0.59
CA2 P00918 5/20 0.59
CA1 P00915 3/20 0.59
KDM6B O15054 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468823 1.00 MME (0.60) MMEACEKDM4EALOX15HIF1A
SCHEMBL29367167 1.00 MME (0.60) MMEACEKDM4EALOX15HIF1A
SCHEMBL9787629 1.00 MME (0.60) MMEACEKDM4EALOX15HIF1A
SCHEMBL9204341 0.91 MME (0.52) MMEACEKDM4EALOX15HIF1A
SCHEMBL14114460 0.89 LCK (0.53) MMEACEKDM4EALOX15HIF1A
SCHEMBL12978378 0.87 CA2 (0.61) MMEACEKDM4EALOX15HIF1A
SCHEMBL22473033 0.87 CA2 (0.61) MMEACEKDM4EALOX15HIF1A
SCHEMBL25396467 0.87 FOLH1 (0.50) MMEACEKDM4EALOX15HIF1A
SCHEMBL468853 0.87 FOLH1 (0.70) MMEACECA2CA1LMNA
SCHEMBL2727938 0.87 ALB (0.54) MMEACEKDM4EALOX15HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US claimed
US-20160200880-A1 MOISTURE CURABLE COMPOSITION WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-07-14 US claimed
EP-3039068-A1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS Momentive Performance Materials Inc. (US) 2016-07-06 EP claimed
WO-2015031712-A1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-03-05 WO claimed
US-RE44302-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-06-18 US claimed
US-RE44017-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-02-19 US claimed
US-RE42902-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2011-11-08 US claimed
US-RE41339-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2010-05-18 US claimed
US-RE41278-E1 N-acetyl aldosamines and related N-acetyl compounds, and their topical use TRISTRATA, INC. 2010-04-27 US claimed
WO-2000040217-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-07-13 WO claimed
EP-0658093-B1 PROCESS AND KIT FOR DYEING HAIR BRISTOL MYERS SQUIBB CO (US) 2000-06-07 EP claimed
EP-0658339-B1 Process and kit for dyeing hair BRISTOL MYERS SQUIBB CO (US) 2000-06-07 EP claimed
US-5628799-A DYE IS A NITROBENZENE SUBSTITUTED WITH AT LEAST ONE NUCLEOPHILIC AMINO GROUP; BUFFER PRESENT; DOPA SPECIES, DYE AND OXIDANT REACT TO FORM MELANIN PRECURSOR WHICH DIFFUSES INTO HAIR TO FORM MELANIN CLAIROL INCORPORATED (US) 1997-05-13 US claimed
EP-0658339-A1 Process and kit for dyeing hair Bristol-Myers Squibb Company (US) 1995-06-21 EP claimed
EP-0658093-A1 PROCESS AND KIT FOR DYEING HAIR Bristol-Myers Squibb Company (US) 1995-06-21 EP claimed
EP-0658093-A4 PROCESS AND KIT FOR DYEING HAIR. BRISTOL MYERS SQUIBB CO (US) 1994-09-23 EP claimed
US-5279617-A Using melanin precursor; oxidizing dopa compound with a ferricyanide salt CLAIROL INCORPORATED (US) 1994-01-18 US claimed
US-5279618-A Forming melanin precursor by reacting dopa with hair dye CLAIROL INCORPORATED (US) 1994-01-18 US claimed
WO-1993005759-A1 PROCESS AND KIT FOR DYEING HAIR BRISTOL-MYERS SQUIBB COMPANY (US) 1993-04-01 WO claimed