Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.50 |
| ▸ | CDC7 | O00311 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874483 | 0.85 | SIRT3 (0.55) | TDP1SIRT3CDC7KDM4EALDH1A1 | |
| SCHEMBL2848389 | 0.83 | KDM4C (0.53) | TDP1KDM4EALDH1A1MEN1KDM6B | |
| SCHEMBL29952392 | 0.83 | KDM4C (0.53) | TDP1KDM4EALDH1A1MEN1KDM6B | |
| SCHEMBL5610674 | 0.83 | TDP1 (0.52) | TDP1SIRT3CDC7KDM4EALDH1A1 | |
| SCHEMBL10639037 | 0.81 | HIPK2 (0.40) | TDP1SIRT3KDM4EALDH1A1MEN1 | |
| SCHEMBL13320901 | 0.81 | MAPT (0.44) | TDP1SIRT3KDM4EALDH1A1MEN1 | |
| SCHEMBL4656245 | 0.79 | HTT (0.38) | TDP1SIRT3CDC7KDM4EALDH1A1 | |
| SCHEMBL4656246 | 0.79 | HTT (0.38) | TDP1SIRT3CDC7KDM4EALDH1A1 | |
| SCHEMBL2847922 | 0.77 | ALDH1A1 (0.58) | TDP1KDM4EALDH1A1KMT2AKDM4C | |
| SCHEMBL29467363 | 0.77 | ALDH1A1 (0.58) | TDP1KDM4EALDH1A1KMT2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092040-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2025-03-20 | — | — | US | disclosed |
| US-20240239797-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
| US-11999730-B1 | AKT1 modulators | ALTEROME THERAPEUTICS, INC. (US) | 2024-06-04 | — | — | US | disclosed |
| US-20240174667-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-05-30 | — | — | US | disclosed |
| US-7709503-B2 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2010-05-04 | — | — | US | disclosed |
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239797-A1 | AKT1 MODULATORS | AKT1S1, AKT1, AKT2 | TDP1 1721/4885SIRT3 2481/4885CDC7 129/4885 |
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | PEF1, PEPD, PELP1 | TDP1 1516/4885SIRT3 2681/4885CDC7 3177/4885 |
| US-20250092040-A1 | AKT1 MODULATORS | AKT1S1, AKT1, AKT2 | TDP1 1721/4885SIRT3 2481/4885CDC7 129/4885 |
| US-11999730-B1 | AKT1 modulators | AKT1S1, AKT1, AKT2 | TDP1 1721/4885SIRT3 2481/4885CDC7 129/4885 |
| US-20240174667-A1 | AKT1 MODULATORS | AKT1S1, AKT1, AKT2 | TDP1 1721/4885SIRT3 2481/4885CDC7 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.