Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adamantane SCHEMBL182780 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2C9 | |
| SCHEMBL2825298 | 0.76 | CYP2C9 (0.31) | CYP2C9 | |
| SCHEMBL1154841 | 0.76 | — | — | |
| SCHEMBL242746 | 0.76 | CYP2C9 (0.31) | CYP2C9 | |
| Bromomethane SCHEMBL4780138 | 0.72 | — | — | |
| Alcohol SCHEMBL3467099 | 0.71 | ALDH1A1 (0.43) | ALDH1A1TSHR | |
| Adamantane SCHEMBL8979787 | 0.71 | CYP2C9 (0.38) | CYP2C9 | |
| Bromide SCHEMBL4768118 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28813180 | 0.71 | — | — | |
| SCHEMBL29107328 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102757319-A | Method for preparing adamantly alkyl vinyl ether | CHONGQING RES INST OF CHEMICAL INDUSTRY | 2012-10-31 | — | — | CN | claimed |
| CN-101830454-B | Selective separation method of diameter of single-wall carbon nano tube | NAT CT NANOSCIENCE NCNST CHINA | 2012-03-07 | — | — | CN | claimed |
| CN-101830454-A | Selective separation method of diameter of single-wall carbon nano tube | NAT CT FOR NANOSCIENCE AND TECHNOLOGY OF CHINA | 2010-09-15 | — | — | CN | claimed |
| CN-102516417-B | Cyclodextrin-based polymers for therapeutics delivery | CERULEAN PHARMA INC | 2014-12-10 | — | — | CN | disclosed |
| CN-102947283-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBOTT LAB | 2013-02-27 | — | — | CN | disclosed |
| CN-101172957-B | Novel compound, synthetic method thereof and therapeutic usage | GILEAD SCIENCES INC (US) | 2012-11-14 | — | — | CN | disclosed |
| CN-102757319-A | Method for preparing adamantly alkyl vinyl ether | CHONGQING RES INST OF CHEMICAL INDUSTRY | 2012-10-31 | — | — | CN | disclosed |
| CN-102516417-A | Cyclodextrin-based polymers for therapeutics delivery | INSERT THERAPEUTICS INC | 2012-06-27 | — | — | CN | disclosed |
| CN-101830454-B | Selective separation method of diameter of single-wall carbon nano tube | NAT CT NANOSCIENCE NCNST CHINA | 2012-03-07 | — | — | CN | disclosed |
| CN-101842359-A | Pyridazinone derivatives and use thereof as p2x7 receptor inhibitors | NISSAN CHEMICAL IND LTD | 2010-09-22 | — | — | CN | disclosed |
| CN-101830454-A | Selective separation method of diameter of single-wall carbon nano tube | NAT CT FOR NANOSCIENCE AND TECHNOLOGY OF CHINA | 2010-09-15 | — | — | CN | disclosed |
| EP-1795548-A1 | CURABLE DIAMANTANE COMPOUND | Tokuyama Corporation (JP) | 2007-06-13 | — | — | EP | disclosed |
| CN-1290881-C | Photosensitive polymer containing adamantyl alkyl vinyl ether and photoresist composition containing the same | SAMSUNG ELECTRONICS CO LTD (KR) | 2006-12-20 | — | — | CN | disclosed |
| US-20060258748-A1 | Diamondoid derivatives possessing therapeutic activity in the treatment of neurologic disorders | CHEVRON U.S.A. INC. (US) | 2006-11-16 | — | — | US | disclosed |
| WO-2006122054-A1 | DIAMONDOID DERIVATIVES POSSESSING THERAPEUTIC ACTIVITY | CHEVRON U.S.A. INC. (US) | 2006-11-16 | — | — | WO | disclosed |
| CN-1861603-A | Silicon phthalocyanine compound and composite, their preparation and application thereof | UNIV FUZHOU (CN) | 2006-11-15 | — | — | CN | disclosed |
| CN-1808272-A | Photosensitive polymers containing adamantylalkyl vinyl ether, and resist compositions including the same | SAMSUNG ELECTRONICS CO LTD (KR) | 2006-07-26 | — | — | CN | disclosed |
| CN-1733707-A | Compounds and methods for synthesis and therapy | GILEAD SCIENCES INC (US) | 2006-02-15 | — | — | CN | disclosed |
| CN-1185223-C | Novel compounds, their synthesis and therapeutic use | GILEAD SCIENCES INC (US) | 2005-01-19 | — | — | CN | disclosed |
| CN-1472231-A | Photosensitive polymer containing adamantyl alkyl vinyl ether and photoresist composition containing the same | 三星电子株式会社 | 2004-02-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258748-A1 | Diamondoid derivatives possessing therapeutic activity in the treatment of neurologic disorders | CLN6, NLN, CDR2 | ALDH1A1 3852/4885TSHR 2747/4885CYP2C9 4771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.