Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347289 | 0.81 | MAPT (0.46) | MAPTGPR35CYP2C9ALDH1A1LMNA | |
| SCHEMBL30413667 | 0.78 | MAPT (0.43) | MAPTGPR35CYP2C19ALDH1A1LMNA | |
| SCHEMBL26133607 | 0.78 | MAPT (0.43) | MAPTGPR35CYP2C19ALDH1A1LMNA | |
| SCHEMBL11815551 | 0.77 | MAPT (0.49) | MAPTCYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL7682478 | 0.73 | MAPT (0.40) | MAPTGPR35CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7496361 | 0.73 | MAPT (0.49) | MAPTALDH1A1LMNAGAACYP1A2 | |
| SCHEMBL2419741 | 0.72 | MAPT (0.38) | MAPTGAAKDM4E | |
| SCHEMBL7493425 | 0.70 | MAPT (0.46) | MAPT | |
| SCHEMBL2586421 | 0.69 | MAPT (0.41) | MAPTGPR35CYP2C9ALDH1A1HIF1A | |
| SCHEMBL2402284 | 0.69 | MAPT (0.41) | MAPTGPR35ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709496-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2010-05-04 | — | — | US | disclosed |
| US-20090054418-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | US | disclosed |
| EP-2007377-A2 | ANTIBACTERIAL AGENTS | Glaxo Group Limited (GB) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118130-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054418-A1 | Antibacterial Agents | MRPL21, ELANE, SPOUT1 | MAPT 4763/4885GPR35 4459/4885CYP2C9 2699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.