Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31171976 | 0.91 | EPHX2 (0.38) | POLBALDH1A1KDM4EHTTGRIN2D | |
| SCHEMBL15257513 | 0.90 | GRIN2D (0.48) | POLBGAAALDH1A1KDM4EHTT | |
| SCHEMBL2438575 | 0.87 | POLB (0.50) | POLBGAAALDH1A1KDM4EHTT | |
| SCHEMBL6159632 | 0.85 | GRIN1 (0.58) | HTTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2443279 | 0.83 | LMNA (0.44) | KDM4ELMNAALKBH5SUCNR1EGLN1 | |
| SCHEMBL1323193 | 0.82 | EPHX2 (0.48) | POLBALDH1A1KDM4EHTTGRIN2D | |
| SCHEMBL6858927 | 0.82 | EPHX2 (0.48) | POLBALDH1A1KDM4EHTTGRIN2D | |
| SCHEMBL18697070 | 0.79 | GRIN2D (0.49) | POLBGAAALDH1A1KDM4EHTT | |
| SCHEMBL10590512 | 0.78 | KDM4E (0.34) | POLBALDH1A1KDM4EHTTLMNA | |
| SCHEMBL6858925 | 0.78 | POLB (0.46) | POLBGAAALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108546224-B | Process for the manufacture of nitriles and their corresponding amines | 中国石化扬子石油化工有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-108546224-B | Process for the manufacture of nitriles and their corresponding amines | 中国石化扬子石油化工有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-8785641-B2 | Synthesis of tripodal catechol derivatives having an adamantyl basic framework for functionalizing surfaces | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2014-07-22 | — | — | US | disclosed |
| EP-2428517-B1 | Synthesis of tripodal bisphosphonate derivatives with an adamantyl base for functionalising surfaces | UNIV GIESSEN JUSTUS LIEBIG (DE) | 2013-11-06 | — | — | EP | disclosed |
| US-20130245269-A1 | Synthesis of Tripodal Catechol Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces | JUSTUS-LIEBIG-UNIVERSITA GIESSEN (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20130217916-A1 | Synthesis of Tripodal Bisphosphonate Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces | JÜSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2013-08-22 | — | — | US | disclosed |
| US-20130217916-A1 | Synthesis of Tripodal Bisphosphonate Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces | JÜSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2013-08-22 | — | — | US | disclosed |
| WO-2012032084-A1 | SYNTHESIS OF TRIPODAL CATECHOL DERIVATIVES HAVING AN ADAMANTYL BASIC FRAMEWORK FOR FUNCTIONALIZING SURFACES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012032089-A1 | SYNTHESIS OF TRIPODAL BISPHOSPHONATE DERIVATIVES HAVING AN ADAMANTYL BASIC FRAMEWORK FOR FUNCTIONALIZING SURFACES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-03-15 | — | — | WO | disclosed |
| EP-2428517-A1 | Synthesis of tripodal bisphosphonate derivatives with an adamantyl base for functionalising surfaces | Justus-Liebig-Universität Gießen (DE) | 2012-03-14 | — | — | EP | disclosed |
| EP-2428502-A1 | Synthesis of tripodal catechol derivatives with an adamantyl base for functionalising surfaces | Justus-Liebig-Universität Gießen (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-8022151-B2 | Adamantane derivative, method for producing the same, resin composition containing the adamantane derivative and use thereof | IDEMITSU KOSAN CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100093947-A1 | ADAMANTANE DERIVATIVE, METHOD FOR PRODUCING THE SAME, RESIN COMPOSITION CONTAINING THE ADAMANTANE DERIVATIVE AND USE THEREOF | IDEMITSU KOSAN CO., LTD. (JP) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245269-A1 | Synthesis of Tripodal Catechol Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces | CHRM1, CHRM5, CHRM4 | POLB 2857/4885GAA 2759/4885ALDH1A1 465/4885 |
| US-20130217916-A1 | Synthesis of Tripodal Bisphosphonate Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces | NR3C2, CHRND, NR3C1 | POLB 1978/4885GAA 3822/4885ALDH1A1 1309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.