Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3285320 | 1.00 | ADORA1 (0.56) | ADORA1SIRT5EGFRFGFR1PTGIR | |
| Trifluoroacetic Acid SCHEMBL3285581 | 1.00 | ADORA1 (0.56) | ADORA1SIRT5EGFRFGFR1PTGIR | |
| Trifluoroacetic Acid SCHEMBL3290829 | 0.87 | ADORA1 (0.50) | ADORA1SIRT5EGFRFGFR1PTGS2 | |
| Trifluoroacetic Acid SCHEMBL3283875 | 0.87 | ADORA1 (0.50) | ADORA1SIRT5PTGS2NTRK1ALDH1A1 | |
| SCHEMBL3285587 | 0.85 | ADORA1 (0.53) | ADORA1SIRT5EGFRFGFR1PTGS2 | |
| SCHEMBL3285586 | 0.85 | ADORA1 (0.53) | ADORA1SIRT5EGFRFGFR1PTGS2 | |
| SCHEMBL3285324 | 0.85 | ADORA1 (0.53) | ADORA1SIRT5EGFRFGFR1PTGS2 | |
| SCHEMBL3290831 | 0.76 | ADORA1 (0.47) | ADORA1SIRT5PTGS2NTRK1HDAC3 | |
| Trifluoroacetic Acid SCHEMBL6496568 | 0.74 | ALDH1A1 (0.44) | RXFP1ALDH1A1CDC25ACDC25B | |
| SCHEMBL3286132 | 0.74 | ADORA1 (0.47) | ADORA1SIRT5HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713988-B2 | 4,5-diphenyl-pyrimidinylamino substituted carboxylic acids, method for the production and use thereof as medicaments | SANOFI-AVENTIS (FR) | 2010-05-11 | — | — | US | disclosed |
| US-20090149487-A1 | 4,5-DIPHENYL-PYRIMIDINYLAMINO SUBSTITUTED CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | SANOFI-AVENTIS (FR) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149487-A1 | 4,5-DIPHENYL-PYRIMIDINYLAMINO SUBSTITUTED CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | GPR119, DPP4, SLC5A1 | ADORA1 478/4885SIRT5 1608/4885EGFR 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.