Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.61 |
| ▸ | ACACA | Q13085 | 2/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CRYAB | P02511 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285804 | 1.00 | ACLY (0.61) | ACLYACACAPTGS1PTGS2PTPN11 | |
| SCHEMBL16411312 | 0.86 | ACLY (0.61) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL17057018 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL21754440 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL13455189 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL23754759 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL10034117 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL20778271 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL560780 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL13420259 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713942-B2 | Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides | NORDIC VACCINE TECHNOLOGY A/S (DK) | 2010-05-11 | — | — | US | disclosed |
| EP-1409009-A1 | THERAPEUTICAL VACCINATION | Nordic Vaccine Technology A/S (DK) | 2004-04-21 | — | — | EP | disclosed |
| EP-1377320-A2 | POLYNUCLEOTIDE BINDING COMPLEXES COMPRISING STEROLS AND SAPONINS | Nordic Vaccine Technology A/S (DK) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002102407-A1 | THERAPEUTICAL VACCINATION | NORDIC VACCINE TECHNOLOGY A/S (DK) | 2002-12-27 | — | — | WO | disclosed |
| WO-2002080981-A2 | POLYNUCLEOTIDE BINDING COMPLEXES COMPRISING STEROLS AND SAPONINS | NORDIC VACCINE TECHNOLOGY A/S (DK) | 2002-10-17 | — | — | WO | disclosed |