Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.61 |
| ▸ | ACACA | Q13085 | 2/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CRYAB | P02511 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285801 | 0.86 | ACLY (0.61) | ACLYACACAPTGS1PTGS2PTPN11 | |
| SCHEMBL3285804 | 0.86 | ACLY (0.61) | ACLYACACAPTGS1PTGS2PTPN11 | |
| SCHEMBL1874653 | 0.85 | ACLY (0.48) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL13644393 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL21754440 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL23754759 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL8283290 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL20778271 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL560780 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 | |
| Cycloartenol SCHEMBL13420259 | 0.85 | ACLY (0.81) | ACLYACACAPTGS1PTGS2PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2829607-B1 | GENE ENCODING OF ENZYME FOR REDUCING POSITION 24 OF STEROID SKELETON AND PLANT HAVING REDUCED EXPRESSION OF SAME GENE | KIRIN HOLDINGS KK (JP) | 2019-08-28 | — | — | EP | disclosed |
| US-9688995-B2 | Gene encoding enzyme that reduces position 24 of steroid skeleton and plant in which expression level of the gene is lowered | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2017-06-27 | — | — | US | disclosed |
| US-20150052635-A1 | GENE ENCODING ENZYME THAT REDUCES POSITION 24 OF STEROID SKELETON AND PLANT IN WHICH EXPRESSION LEVEL OF THE GENE IS LOWERED | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2015-02-19 | — | — | US | disclosed |
| EP-2829607-A1 | GENE ENCODING OF ENZYME FOR REDUCING POSITION 24 OF STEROID SKELETON AND PLANT HAVING REDUCED EXPRESSION OF SAME GENE | Kirin Holdings Kabushiki Kaisha (JP) | 2015-01-28 | — | — | EP | disclosed |