Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 10/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13221081 | 0.87 | PAK1 (0.44) | PAK1IGF1RNTRK1 | |
| SCHEMBL3036860 | 0.87 | PAK1 (0.42) | PAK1IGF1RNTRK1 | |
| SCHEMBL3046927 | 0.87 | SRC (0.42) | PAK1IGF1RNTRK1 | |
| SCHEMBL3288291 | 0.86 | MAP4K2 (0.41) | IGF1R | |
| SCHEMBL3045432 | 0.86 | IGF1R (0.43) | PAK1IGF1R | |
| SCHEMBL3038521 | 0.85 | WDR5 (0.45) | PAK1IGF1R | |
| SCHEMBL13220997 | 0.84 | NEK1 (0.49) | PAK1IGF1R | |
| SCHEMBL3041108 | 0.84 | PAK1 (0.40) | PAK1IGF1R | |
| SCHEMBL13221055 | 0.83 | NEK1 (0.45) | PAK1IGF1R | |
| SCHEMBL3035000 | 0.83 | PAK1 (0.40) | PAK1IGF1RNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713973-B2 | Kinase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-11 | — | — | US | disclosed |