SCHEMBL3286089

SCHEMBL3286089

C=C(CCCC)C(=O)NNCCCC

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 17/20 0.41
HDAC1 Q13547 13/20 0.40
HDAC2 Q92769 13/20 0.40
HDAC8 Q9BY41 5/20 0.40
HDAC6 Q9UBN7 2/20 0.40
NCOR2 Q9Y618 2/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CA12 O43570 1/20 0.36
CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3286700 0.94 HDAC3 (0.41) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL3282425 0.93 HDAC3 (0.43) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL3279719 0.92 HDAC3 (0.41) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL3279664 0.92 CES1 (0.38) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL3280451 0.87 CASP2 (0.44) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL3279306 0.86 CES1 (0.39) CES2CES1
SCHEMBL3278928 0.86 HDAC3 (0.41) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL3279737 0.85 CASP2 (0.47) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL3278185 0.81 HDAC3 (0.42) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL3283264 0.80 HDAC3 (0.42) HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9725589-B2 Method of preparing acrylic polymers and products produced thereby LUBRIZOL ADVANCED MATERIALS, INC. (US) 2017-08-08 US claimed
US-20140336343-A1 Method Of Preparing Acrylic Polymers And Products Produced Thereby LUBRIZOL ADVANCED MATERIALS, INC. 2014-11-13 US claimed
EP-2794672-A1 METHOD OF PREPARING ACRYLIC POLYMERS AND PRODUCTS PRODUCED THEREBY Lubrizol Advanced Materials, Inc. (US) 2014-10-29 EP claimed
WO-2013096206-A1 METHOD OF PREPARING ACRYLIC POLYMERS AND PRODUCTS PRODUCED THEREBY LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-06-27 WO claimed
US-7700540-B2 Hard surface cleaning composition THE CLOROX COMPANY (US) 2010-04-20 US claimed
US-20070099816-A1 Hard Surface Cleaning Composition THE CLOROX COMPANY 2007-05-03 US claimed
US-9725589-B2 Method of preparing acrylic polymers and products produced thereby LUBRIZOL ADVANCED MATERIALS, INC. (US) 2017-08-08 US disclosed
EP-2934678-B1 CARBOXYETHYL ACRYLATE CONTAINING COPOLYMER STABILIZER/THICKENERS AND METHODS TO MITIGATE THE LOSS OF SILICONE DEPOSITION ON KERATINOUS SUBSTRATES LUBRIZOL ADVANCED MAT INC (US) 2017-06-21 EP disclosed
CN-104105714-B Prepare the method and thus obtained product of acrylate copolymer 路博润高级材料公司 2017-04-05 CN disclosed
EP-2794672-B1 METHOD OF PREPARING ACRYLIC POLYMERS AND PRODUCTS PRODUCED THEREBY LUBRIZOL ADVANCED MAT INC (US) 2016-03-23 EP disclosed
US-20150342858-A1 CARBOXYETHYL ACRYLATE CONTAINING COPOLYMER STABILIZER/THICKENERS AND METHODS TO MITIGATE THE LOSS OF SILICONE DEPOSITION ON KERATINOUS SUBSTRATES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-12-03 US disclosed
US-20140336343-A1 Method Of Preparing Acrylic Polymers And Products Produced Thereby LUBRIZOL ADVANCED MATERIALS, INC. 2014-11-13 US disclosed
EP-2794672-A1 METHOD OF PREPARING ACRYLIC POLYMERS AND PRODUCTS PRODUCED THEREBY Lubrizol Advanced Materials, Inc. (US) 2014-10-29 EP disclosed
WO-2013096206-A1 METHOD OF PREPARING ACRYLIC POLYMERS AND PRODUCTS PRODUCED THEREBY LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-06-27 WO disclosed
US-7700540-B2 Hard surface cleaning composition THE CLOROX COMPANY (US) 2010-04-20 US disclosed
US-20070099816-A1 Hard Surface Cleaning Composition THE CLOROX COMPANY 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150342858-A1 CARBOXYETHYL ACRYLATE CONTAINING COPOLYMER STABILIZER/THICKENERS AND METHODS TO MITIGATE THE LOSS OF SILICONE DEPOSITION ON KERATINOUS SUBSTRATES KRT18, SMCHD1, SMURF1 HDAC3 1034/4885HDAC1 477/4885HDAC2 1335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.