SCHEMBL3286142

SCHEMBL3286142

CC(C)[C@@H](NC(N)=O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.46
ALDH1A1 P00352 2/20 0.46
CA2 P00918 4/20 0.43
CA1 P00915 3/20 0.43
GAA P10253 2/20 0.43
LMNA P02545 2/20 0.43
HPGD P15428 1/20 0.43
PLA2G2A P14555 1/20 0.43
PLA2G5 P39877 1/20 0.43
FPR2 P25090 1/20 0.42
NPSR1 Q6W5P4 2/20 0.41
MAPT P10636 1/20 0.41
POLB P06746 2/20 0.40
SLC7A5 Q01650 1/20 0.40
KMT2A Q03164 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4318209 1.00 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1CA2CA1GAA
SCHEMBL6333157 1.00 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1CA2CA1GAA
SCHEMBL28394852 0.83 CA2 (0.45) SMN1; SMN2ALDH1A1CA2CA1
SCHEMBL5496832 0.83 CA2 (0.45) SMN1; SMN2ALDH1A1CA2CA1
SCHEMBL5496834 0.83 CA2 (0.45) SMN1; SMN2ALDH1A1CA2CA1
SCHEMBL5496836 0.83 CA2 (0.45) SMN1; SMN2ALDH1A1CA2CA1
SCHEMBL6664400 0.83 CA2 (0.45) SMN1; SMN2ALDH1A1CA2CA1
SCHEMBL21933694 0.82 POLB (0.41) SMN1; SMN2ALDH1A1LMNAPOLBKMT2A
SCHEMBL9190374 0.81 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1CA2CA1GAA
SCHEMBL9190372 0.81 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1CA2CA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709235-B2 5-Substituted hydantoin racemase, DNA encoding the same, recombinant DNA, transformed cell, and process for production of optically active N-carbamylamino acid or optically active amino acid KANEKA CORPORATION (JP) 2010-05-04 US claimed
US-20080261268-A1 5-Substituted Hydantoin Racemase, Dna Encoding the Same, Recombinant Dna, Transformed Cell, and Process for Production of Optically Active N-Carbamylamino Acid or Optically Active Amino Acid KANEKA CORPORATION (JP) 2008-10-23 US claimed
EP-1852510-A1 5-SUBSTITUTED HYDANTOIN RACEMASE, DNA ENCODING THE SAME, RECOMBINANT DNA, TRANSFORMED CELL, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE N-CARBAMYLAMINO ACID OR OPTICALLY ACTIVE AMINO ACID Kaneka Corporation (JP) 2007-11-07 EP claimed
EP-1209234-A1 STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME Kaneka Corporation (JP) 2002-05-29 EP claimed
US-3941776-A RACEMIZATION OF AMINOLACTAM COMPOUNDS ALLIED CHEMICAL CORPORATION (US) 1976-03-02 US claimed
JP-61047194-A None JP disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
US-5902736-A USING DECARBAMYLASE FROM COMAMONAS, ALCALIGENES, RHIZOBIUM, BLASTOBACTER, SPOROSARCINA, AND BRADYRHYZOBIUM SPECIES IN AQUEOUS MEDIUM; AS CHEMICAL INTERMEDIATES FOR SEMISYNTHETIC PENICILLIN AND CEPHALOSPORIN KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 1999-05-11 US disclosed
US-5863785-A PROTEINS KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 1999-01-26 US disclosed
EP-0801131-A1 PROCESS FOR PRODUCING D-N-CARBAMOYL-$g(a)-AMINO ACID Kanegafuchi Chemical Industry Co., Ltd. (JP) 1997-10-15 EP disclosed
EP-0628637-A1 PROCESS FOR PRODUCING D-$g(a)-AMINO ACID Kanegafuchi Chemical Industry Co., Ltd. (JP) 1994-12-14 EP disclosed
US-4925978-A Method of preparation of optically active alpha-amino-acids ENIRICERCHE S.P.A. (IT) 1990-05-15 US disclosed
JP-S6147194-A PREPARATION OF N-CARBAMOYL-D-VALINE OR D-VALINE MITSUI TOATSU CHEM INC 1986-03-07 JP disclosed
US-4312948-A AGROBACTERIUM CULTURE SNAMPROGETTI S.P.A. (IT) 1982-01-26 US disclosed
JP-S06147194-A 0001-01-01 JP disclosed