SCHEMBL4318209

SCHEMBL4318209

CC(C)[C@H](NC(N)=O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.46
ALDH1A1 P00352 2/20 0.46
CA2 P00918 4/20 0.43
CA1 P00915 3/20 0.43
GAA P10253 2/20 0.43
LMNA P02545 2/20 0.43
HPGD P15428 1/20 0.43
PLA2G2A P14555 1/20 0.43
PLA2G5 P39877 1/20 0.43
FPR2 P25090 1/20 0.42
NPSR1 Q6W5P4 2/20 0.41
MAPT P10636 1/20 0.41
POLB P06746 2/20 0.40
SLC7A5 Q01650 1/20 0.40
KMT2A Q03164 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6333157 1.00 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1CA2CA1GAA
SCHEMBL3286142 1.00 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1CA2CA1GAA
SCHEMBL28394852 0.83 CA2 (0.45) SMN1; SMN2ALDH1A1CA2CA1
SCHEMBL5496832 0.83 CA2 (0.45) SMN1; SMN2ALDH1A1CA2CA1
SCHEMBL5496834 0.83 CA2 (0.45) SMN1; SMN2ALDH1A1CA2CA1
SCHEMBL5496836 0.83 CA2 (0.45) SMN1; SMN2ALDH1A1CA2CA1
SCHEMBL6664400 0.83 CA2 (0.45) SMN1; SMN2ALDH1A1CA2CA1
SCHEMBL21933694 0.82 POLB (0.41) SMN1; SMN2ALDH1A1LMNAPOLBKMT2A
SCHEMBL9190374 0.81 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1CA2CA1GAA
SCHEMBL9190372 0.81 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1CA2CA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1209234-A1 STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME Kaneka Corporation (JP) 2002-05-29 EP claimed
EP-0469739-B1 Stationary phase for enantiomeric resolution in liquid chromatography SHIMADZU CORP (JP) 1994-06-15 EP claimed
US-5149426-A Stationary phase for enantiomeric resolution in liquid chromatography SHIMADZU CORPORATION (JP) 1992-09-22 US claimed
EP-0469739-A1 Stationary phase for enantiomeric resolution in liquid chromatography SHIMADZU CORPORATION (JP) 1992-02-05 EP claimed
US-3941776-A RACEMIZATION OF AMINOLACTAM COMPOUNDS ALLIED CHEMICAL CORPORATION (US) 1976-03-02 US claimed
JP-61050956-A None JP disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
CN-109569532-B Separating agent 株式会社大赛璐 2021-12-14 CN disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
EP-0469739-B1 Stationary phase for enantiomeric resolution in liquid chromatography SHIMADZU CORP (JP) 1994-06-15 EP disclosed
US-5149426-A Stationary phase for enantiomeric resolution in liquid chromatography SHIMADZU CORPORATION (JP) 1992-09-22 US disclosed
EP-0469739-A1 Stationary phase for enantiomeric resolution in liquid chromatography SHIMADZU CORPORATION (JP) 1992-02-05 EP disclosed
EP-0381997-A1 Microbially prepared N-acetyl-2,3-didehydroleucine acylase, process for its preparation and its use Degussa Aktiengesellschaft (DE) 1990-08-16 EP disclosed
EP-0152977-B1 PROCESS FOR THE PREPARATION OF L-ALPHA-AMINOACIDS SCLAVO S.p.A. (IT) 1988-07-20 EP disclosed
JP-S6150956-A METHOD OF OPTICAL RESOLUTION OF (+-)-N-CARBAMOYL-VALINE NITTO CHEM IND CO LTD 1986-03-13 JP disclosed
EP-0152977-A1 Process for the preparation of L-alpha-aminoacids SCLAVO S.p.A. (IT) 1985-08-28 EP disclosed
US-3964970-A Process for the preparation of L-car-bamyl-amino acids and of the corresponding L-amino acids SNAM PROGETTI S.P.A. (IT) 1976-06-22 US disclosed